Inflammatory bowel disease consists of ulcerative colitis and Crohn's disease.
Ulcerative colitis is a diffuse mucosal inflammation limited to the colon while Crohn's disease is a patchy, transmural inflammation that occurs in any part of the gastrointestinal tract.
The ileum and colon are the most frequently affected sites.
In the treatment of patients with Crohn’s disease or ulcerative colitis, adding an immunomodulator to ustekinumab or vedolizumab has a null effect on key outcomes, including clinical remission or response, endoscopic remission, and persistence of therapy at 1 year, as shown in a study.
Patients with Crohn’s disease risk developing osteoporosis and related fractures, but this may be countered by performing combined impact and resistance training exercises, which confer benefits for bone mineral density and muscle function, a study has shown.
Use of cannabis or cannabinoids among patients with inflammatory bowel disease (IBD) does little to induce clinical remission or reduce inflammation, although it helps calm patient-reported symptoms and improve quality of life, a study has found.
The presence of anxiety and mood disorders appears to interfere with treatment adherence among inflammatory bowel disease (IBD) patients initiating anti-tumour necrosis factor therapy, a study has found.
Patients with inflammatory bowel disease (IBD) have more than a twofold risk of developing dementia, according to a study, implicating gut–brain axis and chronic inflammation in progressive neurocognitive degeneration.
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Percutaneous coronary intervention (PCI), compared with coronary artery bypass grafting (CABG), in the revascularization of left main coronary artery (LMCA) disease may lead to death, myocardial infarction (MI), or stroke in patients with moderate or severe left ventricular (LV) dysfunction, reveals a study.