Inflammatory bowel disease consists of ulcerative colitis and Crohn's disease.
Ulcerative colitis is a diffuse mucosal inflammation limited to the colon while Crohn's disease is a patchy, transmural inflammation that occurs in any part of the gastrointestinal tract.
The ileum and colon are the most frequently affected sites.

Differential Diagnosis

  • Differential diagnoses include diseases that may mimic UC or CD

Infectious Diseases

  • Bacterial (intestinal TB, Yersinia sp), fungal (Actinomycosis), viral (Lymphogranuloma venereum, CMV), or protozoal (schistosomiasis, amoebiasis)

Noninfectious Diseases

  • Behcet’s disease
  • Irritable bowel syndrome
  • Colon cancer
  • Diverticulitis: Fever, abdominal pain, tender abdominal mass, leukocytosis, elevated ESR, partial obstruction and fistulas
  • Intestinal lymphoma
  • Ischemic colitis: Transmural scarring, stricture formation
  • Lactose intolerance: Diarrhea, abdominal pain, flatulence after ingestion of milk or milk-containing products
  • Effects of radiation therapy: Bloody, mucoid diarrhea and tenesmus 1-2 weeks after irradiation of rectum and sigmoid, stricturing, fistula formation, malabsorption and weight loss
  • Drug-induced colitis
    • NSAIDs: Diarrhea, abdominal pain, stricture, bleeding, obstruction, perforation and fistulization
    • Retinoic acid, gold, oral contraceptives
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
06 Sep 2018
Suicide appears to be more common in patients with cancers of the digestive system, especially in those with pancreatic and oesophageal cancers, a recent study has found.
19 Jul 2016
In this series, we present authoritative advice on the investigation of a common clinical problem, especially commissioned for family doctors and written by members of the Royal Australasian College of Physicians.
08 Sep 2018
Use of statins may reduce the severity of acute pancreatitis (AP) seen in the decrease of overall incidence of multisystem organ failure (MSOF) and new MSOF, suggests a recent study.
12 Sep 2018
Hospitalization for acute biliary pancreatitis in elderly patients is likely to lead to adverse clinical outcomes, according to a study.