Infective endocarditis is microbial infection of the endovascular structures of the heart.
It often presents in an occult fashion and early diagnosis depends on a high index of clinical suspicion especially in patients with congenital heart disease, prosthetic valves or previous infective endocarditis.
The established diagnosis of infective endocarditis is demonstrated by a positive blood culture and involvement of the endocardium detected during sepsis or systemic infection. It may also be established if there is involvement of the endocardium detected during sepsis or systemic infection but blood culture is negative.

Differential Diagnosis

Alternative Diagnosis

  • Diagnose & treat patient appropriately for other disease states (eg atrial myxoma, SLE w/ marantic endocarditis, acute rheumatic fever & cardiac syndrome) presenting w/ similar signs & symptoms

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