Infective endocarditis is an infection of the endocardial surface of the heart including infections of the large thoracic vessels and intracardiac foreign bodies characterized by the presence of vegetation which is a nidus for microorganism invasion.
Native valve endocarditis is an endovascular microbial infection of native heart valves that may be local including valvular and perivalvular destruction or distal due to detachment of septic vegetations with embolism, metastatic infection and septicemia.
Prosthetic valve endocarditis is an endovascular microbial infection of prosthetic heart valves and may be classified as an infection likely to have been acquired perioperatively and thus being nosocomial or likely to have been community-acquired.
Diagnose & treat patient appropriately for other disease
states (eg atrial myxoma, systemic lupus erythematosus with marantic endocarditis, acute rheumatic
fever & cardiac syndrome) presenting with similar signs & symptoms
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Antibiotics has been administered unnecessarily to as many as one-third of children with respiratory syncytial virus (RSV) lower respiratory tract infections (LRTI) in hospitals in the Netherlands and Israel, according to a prospective international multicentre RSV study using an expert panel as reference standard to identify children with and without bacterial coinfection.
Antibiotic therapy in preterm, very low birth weight (VLBW) infants within the first 14 postnatal days increases the risk of subsequent late-onset sepsis, necrotizing enterocolitis (NEC) or death, a recent study has shown.