People living with HIV (PLHIV) are often uncomfortable talking to their healthcare providers (HCPs) about issues related to their condition, reports a new study presented at the recently concluded 2020 IDWeek Virtual Conference (ID Week 2020). In turn, PLHIVs tend to suffer from worse quality of life (QOL).
During the earliest days of the novel coronavirus disease (COVID-19) pandemic, convalescent plasma has generated great enthusiasm for its potential in treating the disease, but a recent study shows that its use does not lead to reduction in progression to severe COVID-19 or all-cause mortality.
In highly viraemic mothers, initiating treatment with tenofovir alafenamide fumarate (TAF) at the 13th gestational week or later in pregnancy puts a lid on hepatitis B virus (HBV) and prevents vertical transmission when infants receive standard immunoprophylaxis, as shown in a study.
Looking at internet search patterns could help authorities stay one step ahead of the novel coronavirus disease (COVID-19), according to a recent study. In the future, internet surveillance and keyword trends may be leveraged for infectious disease control.
Application for Sputnik V, the tradename of the world’s first registered COVID-19 vaccine, has been submitted to the WHO for accelerated registration via the Emergency Use Listing (EUL) and prequalification.
Commuters who had been exposed to an index case with COVID-19 during a bus journey were 42 times more likely to be infected than control riders in another bus of similar journey — adding further evidence to the notion that airborne transmission of the virus is possible, especially in an enclosed area.
The incidence of chest radiograph (CXR) abnormality appears to be lower in a cohort of swab-positive coronavirus disease (COVID-19) patients, including those identified from contact tracing, than previously reported, a Singapore study has found. Ground-glass opacity or consolidation was the predominant pattern, but mixed central and peripheral involvement is more common than peripheral involvement alone.
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).
A trial vaccine for the prevention of COVID-19 is underway with the first US participants being dosed in the Phase 1/2 clinical trial. Known as the BNT162 vaccine programme, the trials are a collaboration between Pfizer Inc. and BioNTech SE, and is part of a global development programme with Germany and the US taking the lead in having the first cohorts to be vaccinated. Germany started the study 1 week earlier.
Rinsing with mouthwash that contains povidone-iodine (PI) or cetylpyridinium chloride (CPC) helps reduce SARS-CoV-2 levels in the saliva of COVID-19 patients, with the effect persisting for up to 6 hours, as shown in a study from Singapore.