Sustained virologic response (SVR) rates with a 12-week course of ribavirin therapy appear to be lower than expected in an Asian cohort of transplant recipients with hepatitis E virus (HEV) infection, with those who received kidney transplant as opposed to other organs being more likely to fail therapy, as reported in a recent study from Singapore.
A quadruple combination antiretroviral therapy (cART) demonstrates similar effects when compared to a triple cART in treatment-naïve people with HIV, according to the results of a systematic review and meta-analysis.
Using point-of-care testing (POCT) of C-reactive protein (CRP) to guide antibiotic prescribing in primary care clinics led to reduced antibiotic use for acute exacerbations of chronic obstructive pulmonary disease (COPD) without compromising clinical outcomes, the PACE* study finds.
Children with noncritical infections and no gastrointestinal symptoms show similar gut and innate immune cell alterations as those with severe sepsis or organ failure, according to a study. Such changes are associated with increased morbidity and mortality and with a higher risk of future infections.
At its current prices, the use of direct-acting antivirals (DAA) as first-line therapy for genotype 3 hepatitis C virus (HCV) in Singapore is not cost-effective, especially as compared to pegylated interferon and ribavirin, according to a new study.
Women who receive a single dose of amoxicillin and clavulanic acid within 6 hours of operative vaginal delivery could significantly reduce their postpartum infection risk, according to the UK-based ANODE* trial.
Infection could be a risk factor for stroke, with the risk for ischaemic stroke particularly high among individuals who had a urinary tract infection (UTI) 7 days prior, according to a recently published report.
Catching any type of infection, including those that affect the urinary and respiratory tracts and sepsis, could increase the chances of having subsequent acute ischaemic stroke, according to a recent study.
Infection with Corynebacteria, antibiotic treatment for a previous episode of granulomatous mastitis, and presenting with inflammatory symptoms may increase the risk for granulomatous mastitis recurrence, according to a retrospective study from Singapore.
The risk of serious infection* among patients receiving systemic therapy for psoriasis differs by treatment, with apremilast, etanercept, and ustekinumab associated with a reduced risk of serious infection than methotrexate, according to an observational study.
Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.
The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.