A 48-week course of combination therapy with pegylated interferon and tenofovir disoproxil fumarate appears to induce functional cure in patients with chronic hepatitis B, leading to a remarkable reduction in viral surface antigen levels (HBsAg) in the blood, according to real-world data.
Initiation of methotrexate appears to lower the risk of infection in patients with sarcoidosis at 6 months as compared to azathioprine, suggest the results from the emulation of a target trial with pre-existing data. However, the favourable effect of methotrexate is attenuated at 9 months.
Short-term use of either oral hydroxychloroquine (HCQ) and povidone-iodine throat spray have shown a signal of reducing the incidence of SARS-CoV-2 infection among young men living in a closed and high-exposure setting, with either compound being superior to oral vitamin C, as shown in an open-label trial from Singapore.
Most healthcare workers (HCWs) in Singapore fear contracting COVID-19 but remain committed to accept the risk of viral transmission despite perceiving a moderate-to-high risk of contracting the disease during the course of their work, a recent survey has shown.
Older adults and elderly individuals are still more susceptible to acquiring COVID-19 infection than younger individuals, even if individuals from both age groups stayed in the same household, a Singapore study has shown.
The Artificial Breathing Capability Device, or ABCD, has been shown to be safe, efficacious, and cost-effective option for respiratory support, according to a study. It can be considered for adults and children when there is a shortage of ventilators especially during the COVID-19 pandemic.
Amidst the optimism from COVID-19 vaccine roll-out, the irrepressible yearning for normalcy is unmistakable. People are starting to drop their guard, thronging malls, and snapping up cruise tickets as soon as they become available.
High doses of zinc gluconate, ascorbic acid, or both do not shorten the duration of COVID-19 symptoms more than standard of care (SoC) in outpatients diagnosed with SARS-CoV-2, according to results of the prospective COVID A to Z trial.
Incidence of multiorgan dysfunction is higher among individuals discharged from hospital after COVID-19 than among those in the general population, and this relative risk increase is not confined to the elderly and not uniform across ethnicities, a study has found.