Doubling the frequency of influenza vaccination from annually to twice a year can increase strain-specific antibody titres and was associated with a reduced incidence of symptomatic respiratory illness, according to the TROPICS1* study.
New drug applications approved by US FDA as of 1 - 15 October 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
A new patch comprising autologous leucocytes, platelets, and fibrin improved the healing rate of hard-to-heal foot ulcers among patients with diabetes compared with standard therapy, a recent study found.
Patients at risk of urinary tract infections (UTIs) are also highly likely to experience excessive weight gain, with risk factors including persistent reflux, younger age and Hispanic/Latino ethnicity, according to a secondary analysis of two prospective studies.
Newer molecular tests for high-risk human papillomavirus (hrHPV) may provide a cost-effective means for cervical cancer screening for low-to-middle income countries (LMICs), with results comparable to cervical biopsies.
The implementation of point-of-care testing (POCT) for viral respiratory infections in emergency departments could reduce unnecessary hospitalizations and antibiotic treatment, according to a study from the UK.
Children who are undergoing intensive chemotherapy for acute leukaemia could benefit from prophylactic levofloxacin which appeared to reduce their risk of developing bacteraemia, according to a recent study by the Children’s Oncology Group. However, prophylactic levofloxacin did not have the same effect in children undergoing haematopoietic stem cell transplantation (HSCT).
Single doses of the small-molecule prodrug baloxavir marboxil (hereafter baloxavir) was effective in alleviating influenza symptoms and superior to oseltamivir in reducing infectious viral load within 1 day after initiating treatment in people with uncomplicated influenza, results of two randomized trials show.
Hepatitis D virus infection is highly prevalent in subgroups of individuals with intravenous drug use and those with high-risk sexual behaviour, study has reported. Its prevalence has also increased twofold over time in patients infected with hepatitis B virus.
The nucleotide analogue tenofovir disoproxil fumarate (TDF) is associated with mild renal impairment in a minority of patients being treated for chronic hepatitis B virus (HBV) infection, a study by the Chinese University of Hong Kong (CUHK) has shown.
A US study suggests that expanding HIV screening to reduce undiagnosed infections and increasing access to care and treatment to achieve viral suppression are important to lessen HIV transmission. It is also imperative that prevention methods, such as condoms and pre-exposure prophylaxis, be easily accessed, particularly among young men who have sex with men (MSM) and MSM of colour.