A single infusion of infliximab effectively resolves fever in paediatric patients with acute Kawasaki disease (KD) refractory to conventional therapies, a Japan study performed in the real-world clinical setting has shown. In addition, it is well tolerated, with no new safety concerns seen.
In chronic obstructive pulmonary disease (COPD) patients initiating inhaled corticosteroid (ICS)/long-acting β2 agonist (LABA) combinations, both budesonide/formoterol (FOR) dry-powder inhalers and beclomethasone/FOR metered-dose inhalers pose lower risks of severe pneumonia and severe adverse events compared with fluticasone/salmeterol delivered using the same type of inhaler, as reported in a recent study.
Older patients and those with haemato-oncology conditions are less likely than surgical patients to be referred to infectious disease (ID) physicians within 48 hours of hospital admission. Furthermore, they appear to be more likely to require antibiotic stewardship programmes (ASP) due to inappropriate type or duration of antibiotic therapy despite ID consultations, a retrospective cross-sectional study from Singapore showed.
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
The World Antibiotic Awareness Week took place in November 2019 and in conjunction with the event, the Antimicrobial Resistance Summit Expert Group and the Antimicrobial Stewardship Working Group convened in Bangkok, Thailand, in the final weekend of October.
Prophylactic treatment with caspofunginmayreduce the incidence of invasive fungal disease (IFD) in children, adolescents, and young adults (AYAs) with acute myeloid leukaemia (AML) compared with fluconazole, according to a recent study.
Dr Dariusz P. Olszyna, a senior consultant at the Division of Infectious Diseases, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the importance of early detection to prevent the spread and complications related to sexually-transmitted infections (STIs).
A significant number of paediatric patients in Singapore who have been hospitalized for measles infection present with nonspecific symptoms at an early phase of illness, which makes it difficult to properly isolate all potential suspected measles patients in the emergency department (ED) setting despite strict isolation policies, according to a study.