In patients hospitalized with COVID-19, hypernatraemia during hospitalization may increase mortality risk, while hyponatraemia at admission may up the need for ventilation support, a recent study from the UK showed.
Data from two centres in Israel support short-term safety of the BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine in cancer patients treated with immune checkpoint inhibitors (ICIs), including those with previous immune-related side effects from ICIs.
An evaluation of the cost-effectiveness of two rotavirus vaccines, carried out by researchers in Hong Kong, the UK and the US, shows that vaccination is likely to be cost-saving to the Hong Kong government and payers.
Neutralizing antibody response against SARS-CoV-2 can be categorized into five patterns of response, with persistent neutralizing antibodies being correlated with severe COVID-19 disease and higher pro-inflammatory cytokine levels, according to a Singapore study.
Incidence of multiorgan dysfunction is higher among individuals discharged from hospital after COVID-19 than among those in the general population, and this relative risk increase is not confined to the elderly and not uniform across ethnicities, a study has found.
Exposure to angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) does not appear to increase the risk of being diagnosed with COVID-19 or hospitalization for COVID-19–related outcomes, according to a study.
The novel box-type device Endoshield can help prevent the spread of the novel coronavirus disease (COVID-19) during paediatric endoscopic procedures, according to a Thailand study. This protective barrier is affordable, usable, and is suitable for use both at the left lateral and supine positions.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.