An 8- or 12-week regimen of glecaprevir plus pibrentasvir appears to be safe and effective in the treatment of genotype 2 hepatitis C virus (HCV) infection in patients undergoing haemodialysis, as reported in a recent Japanese cohort study.
Bloodstream infections are common among patients with epidermal necrolysis and are mostly caused by Staphylococcus aureus and Pseudomonas aeruginosa, a recent study has found. Skin cultures may help predict such infections.
Hepatitis C virus (HCV) transmission from infected children to other relatives happens, and the only documented way of transmission either directly or indirectly is through parenteral route, a recent study has found.
An investigational bivalent Clostridium difficile vaccine that contains equal dosages of genetically and chemically detoxified toxins A and B has a tolerable safety profile and is immunogenic in healthy older adults, according to the results of a phase II trial.
One in four cases of Gram-negative bacilli (GNB) bloodstream infection (BSI) is multidrug-resistant, a new study has found. Risk factors for multidrug-resistant GNB BSI in children’s hospitals include cancer chemotherapy and older age. Multidrug resistance, however, does not seem to increase the rate of all-cause mortality.
New drug applications approved by US FDA as of 01 - 15 November 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Streptococcus anginosus, aminoglycoside-susceptible Gram-negative bacilli and anaerobes remain the most common bacteria in previously healthy children presenting with complicated appendicitis requiring surgical drainage, reports a study.