Systemic neonatal infections appear to affect the developing brain, such that its presence in term-born infants with cerebral palsy (CP) is associated with severe phenotypic presentation, a recent study has shown.
Use of antiviral treatment for colonic cytomegalovirus (CMV) infection significantly improves short- and long-term surgery-free survival in patients with ulcerative colitis (UC), according to the results of a small-scale study.
Apart from being tolerable and feasible, pre- and post-transplantation hepatitis C virus (HCV) treatments prevent HCV infection in non–HCV-infected recipients (ie, HCV D+/R− transplantation) of kidneys, a recent open-label nonrandomized trial in a single centre has shown.
There appears to be no association between pandemic influenza vaccination and the risk of epilepsy among children, according to a study, which suggests concerns about the vaccination may be unwarranted.
The use of shorter treatment regimens in children with tuberculosis (TB) infection leads to increased rates of completion and fewer adverse events when compared with 9 months of daily isoniazid treatment, a study has shown.
Elderly adults hospitalized for fever or respiratory syndromes are much less likely than younger adults to be recommended for influenza testing, a recent study has shown. This is partly explained by a lower likelihood to present with influenza-like illnesses.
In patients with chronic hepatitis B virus (HBV) infection, tenofovir alafenamide (TAF) shows comparable 96-week efficacy and improved renal and bone safety with tenofovir disoproxil fumarate (TDF), a recent study has shown.
The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.
The addition of low oxygen levels measured by pulse oximetry to the three signs delineated in the current diagnostic model for pneumonia in primary care setting derived by van Vugt, which include fever, tachycardia, and crackly breath sounds on auscultation, can add value to diagnostic precision and help general practitioners (GPs) differentiate pneumonia from less serious infections, a study suggests.
Ceftazidime-avibactam appears to offer a reasonable alternative to colistin in the treatment of Klebsiella pneumoniae carbapenemase (KPC)-producing carbapenem-resistant Enterobacteriaceae (CRE) infections, according to a study.