Isoniazid preventive therapy is safe to use in pregnant women with HIV, especially those with a CD4 count <350 cells/μl, conferring protection against incident tuberculosis (TB) without deleterious maternal and foetal consequences, a study has shown.
An inpatient faecal microbiota transplantation programme yields substantial reductions in Clostridioides difficile infection (CDI)-related mortality in patients with refractory severe or fulminant (SF) CDI, a study has found.
A 10-day or 14-day sequential therapy strategy is more cost-effective than a conventional triple therapy in the management of patients with Helicobacter pylori infection, in addition to being more effective in terms of eradication of infection, as reported in a study from Egypt.
In children with recurrent acute otitis media (rAOM), the presence of bacterial otopathogen, particularly nontypeable H. influenzae (NTHi), in the middle ear during ventilation tube insertion (VTI) is associated with repeat surgery, according to a recent study.
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
The angiotensin receptor blocker (ARB) losartan did not improve inflammation, T-cell immune recovery, or fibrotic activity among older persons living with HIV (PLHIV) and viral suppression, according to data presented at CROI 2020.