Tuberculosis (TB) patients with high blood pressure are at increased risk of death during the 9 months following initiation of treatment, a study has found. But the good news is that dihydropyridine calcium channel blockers (DHP-CCBs) may improve survival outcomes.
Faecal microbiota transplantation (FMT) response may be sustained even after being exposed to Clostridioides difficile infection (CDI) risk factors, such as comorbidities and use of systemic antibiotics or acid suppressant medications, among others, a study reports. Antibiotic use post-FMT is predictive of response loss.
Use of pegylated interferon alpha 2a as an add-on therapy in chronic hepatitis B patients on tenofovir disoproxil fumarate facilitates rapid reductions in hepatitis B surface antigen (HBsAg) and core-related antigen (HBcrAg) levels, a study has shown.
In the treatment of cytokine storm syndrome due to the coronavirus disease (COVID-19), administering tocilizumab via the intravenous (IV) route appears to be more effective than subcutaneous (SC) therapy, leading to earlier symptom improvement and better survival, according to a study.
In paediatric patients with microbial keratitis, the most significant risk factors are contact lens wear, trauma, and existing ocular disease, while pre-existing corneal disease and delay in presentation correlate with poor visual acuity, according to a study.
A substantial proportion of COVID-19 patients shed SARS-CoV-2 viral RNA in faeces, with the virus persisting long after respiratory testing has become negative, according to the results of a meta-analysis. This suggests that the disease can be spread via the faecal–oral route.
Application for Sputnik V, the tradename of the world’s first registered COVID-19 vaccine, has been submitted to the WHO for accelerated registration via the Emergency Use Listing (EUL) and prequalification.