Adolescents with chronic hepatitis C virus (HCV) infection are prone to develop significant fibrosis, including cirrhosis, reveals a study. Serum biomarkers aspartate transaminase-to-platelet ratio index (APRI) and Fibrosis-4 index (FIB-4) are positively associated with liver stiffness measurement (LSM).
Bidirectional contact tracing, wherein both parent and subsequent cases of a known infected patient, could help drastically improve control of the coronavirus disease 2019 (COVID-19) pandemic, a recent study reports.
Bezlotoxumab is both safe and effective for the prevention of recurrent Clostridioides difficile infection (rCDI), results of a meta-analysis have shown. Moreover, bezlotoxumab may be a good therapeutic option for severe rather than mild CDI.
An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.