Various biologic medications used prior to total knee or hip arthroplasty demonstrate similar risks for hospitalized infection, prosthetic joint infection (PJI) and readmission after surgery, reports a study. In contrast, glucocorticoids, particularly with dosages >10 mg/d, yield a greater risk for adverse outcomes.
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
A two-step algorithm that incorporates the liver stiffness measurement hepatocellular carcinoma (LSM-HCC) score and enhanced liver fibrosis (ELF) score appears to improve the accuracy of predicting HCC in chronic hepatitis B (CHB) patients after antiviral treatment, according to a study from Hong Kong.
Adding bismuth to a 14-day course of standard triple therapy with clarithromycin and amoxicillin leads to a high rate of Helicobacter pylori infection eradication, with an acceptable safety profile and level of adherence, according to a study.
An Israel study provides evidence of a low short-term paediatric mortality after Staphylococcus aureus (SA) bacteraemia, as well as an increased long-term mortality risk for healthcare-associated (HA) SA, particularly in children with chronic diseases.