Hepatitis C virus (HCV) treatment may benefit patients with HCV-related hepatocellular carcinoma (HCC) who respond to the initial HCC palliative treatment, suggest the results of a study, adding, however, that treating HCV in HCC patient undergoing noncurative HCC treatment remains debatable.
Higher doses of rifampin result in more rapid sputum sterilization and similar toxicity, a study has shown. These findings support the investigation of increased rifampin doses to shorten tuberculosis treatment.
In children with moderate or severe asthma exacerbations, the presence of respiratory pathogens such as respiratory syncytial virus, influenza and parainfluenza appears to increase the risk of treatment failure, a study reports.
A pseudomembrane-driven faecal microbiota transplantation protocol comprising multiple faecal infusions and concomitant vancomycin proves to be more effective than a single faecal transplant followed by vancomycin for treating severe Clostridium difficile infection (CDI) refractory to antibiotics, a study has shown.
Infants born to mothers with rheumatoid arthritis treated with tumour necrosis factor inhibitors (TNFIs) during pregnancy do not have a heightened risk of developing serious infections, a study reports.
Recurrent acute uncomplicated urinary tract infection (UTI) negatively affects quality of life (QOL), including physical and mental health status, in premenopausal women, according to a study. QOL may even be lower in UTI-infected women with comorbid chronic constipation or who consume caffeine.
The fatality of hand, foot and mouth disease associated with enterovirus 71 increased in the period of 2008-2012 compared with the number of cases in 1998-2007 based on a systematic review and meta-analysis.
High school girls (15 to 19 years) on long-acting reversible contraception (LARC) are 60 percent less likely to use condoms compared to contraceptive pill users, findings of a US-based study. This places these girls and their partners at a higher risk for sexually transmitted infections (STIs) including human immunodeficiency virus and reflects their ignorance that condoms are mainly used for pregnancy prevention.