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Top Medical News
Women who receive their first catch-up dose of the human papillomavirus (HPV) vaccination at a younger age may obtain the most benefits in terms of cancer protection, according to a recent study.
Tuberculosis (TB) is an important adverse event associated with the use of biologics, especially antitumour necrosis factor, in the management of autoimmune inflammatory rheumatic diseases, according to a study. Prophylaxis can effectively reduce the risk in patients testing positive for latent TB at screening.
Initial treatment with intravenous immunoglobulin (IVIG) plus infliximab lessens the need for additional therapy in Kawasaki disease (KD) patients presenting with coronary artery lesions (CALs), a recent study has shown.
It is safe to revaccinate patients with a history of mild or moderate adverse events following immunization (AEFI), but more research is required in those with serious AEFIs who are less likely to be reimmunized, suggests a recent study.
Prophylactic antibiotic therapy appears to be beneficial to older adults with recurrent urinary tract infection (UTI), reducing clinical recurrence and acute antibiotic prescribing, a study reports.
In patients receiving foecal microbiota transplantation (FMT) for the treatment of Clostridium difficile infection (CDI), high levels of Candida albicans may be associated with poor outcomes, a recent study has shown.
A simple instrument that uses thermistor-based breathing sensors can accurately measure respiratory rate (RR) in children, as well as in adults, holding great potential for diagnosing paediatric pneumonia in low-resource settings, according to a study.
Special Reports
Influenza is a highly contagious viral disease, which is primarily spread through water droplets containing strains of the virus. Dr Leong Chee Loon shares his insights into the management of influenza in Malaysia, highlighting the importance of improving vaccination coverage in populations at high-risk of influenza-related complications, such as elderly patients and healthcare practitioners.
ZEPATIER - Elbasvir 50 mg, grazoprevir 100 mg FC tab - Merck Sharp & Dohme
At the 13th Asian Congress of Paediatric Nephrology 2017 in conjunction with the 39th Malaysian Paediatric Association Annual Congress, Dr Wanatpreeya Phongsamart spoke on the importance of influenza vaccination in children, highlighting the role of quadrivalent influenza vaccine (QIV) in providing a broader protection against influenza. Meanwhile, Emeritus Professor Somsak Lolekha shared his insights into the effectiveness of a hexavalent vaccine in paediatric immunization, and discussed its role in the Malaysian paediatric immunization schedule.
At a continuing medical education webcast hosted by GlaxoSmithKline, Dr Gyneth Lourdes G. Bibera discussed on preventive strategies against rotavirus gastroenteritis (RVGE).
Fluarex Tetra - Inactivated quadrivalent influenza vaccine (split virion) vaccine (inj) 0.5 mL - GlaxoSmithKline
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia.
DUKORAL – Inactivated Vibrio cholerae O1 serogroup & recombinant cholera toxin B subunit (WC/rCTB) vaccine (oral) – AJ Biologics
Conference Reports
Teenagers and young adults living with perinatally acquired HIV (PaHIV) have a higher risk of developing malignancies and a higher all-cause mortality rate than their non-HIV-infected peers, according to a study from the UK.
Restoration of CD4/CD8 ratio on combination antiretroviral therapy (cART) was associated with decreased risk of Kaposi sarcoma (KS) while baseline CD8 count was related to non-Hogkin lymphoma (NHL) risk in people living with HIV (PLHIV) who had achieved viral suppression on cART, according to the COHERE* study presented at the AIDS International Conference (AIC) 2018.
Use of triple antiretroviral therapy (ART) during pregnancy and breastfeeding did not affect the cognitive development and function of the offspring compared with those whose mothers were not exposed to ART, reveals the IMPAACT PROMISE-BF study presented at the IAC 2018.
The combination of dolutegravir + lamivudine appeared noninferior to dolutegravir + tenofovir/emtricitabine in reducing viral load in treatment-naïve patients with HIV-1 infection, according to the phase III GEMINI-1 and GEMINI-2* trials presented at AIDS 2018.
Simplification from combination antiretroviral therapy (cART) to dolutegravir monotherapy as maintenance treatment was noninferior to continuing therapy with cART, at least in patients who initiated cART during primary HIV infection and had achieved suppressed viral load for ≥48 weeks, suggests a study presented at IAC 2018.
What is undetectable is untransmittable, and this extends to HIV risk in serodiscordant gay couples on effective antiretroviral treatment (ART), the PARTNER 2 study has shown.
Online HIV self-testing may provide a channel for men who have sex with men (MSM) and transgender women (TGW) to access treatment, according to a Thai study presented at AIDS 2018.
