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Oral noninferior to intravenous antibiotic therapy for complex orthopaedic infection

2 hours ago

The oral route of administration for antibiotics appears to be as effective as the intravenous route during the first 6 weeks of treatment of complex orthopaedic infection, according to the results of a trial.

Enterovirus infection during early childhood triggers coeliac disease

Stephen Padilla, Yesterday

A higher frequency of enterovirus, but not adenovirus, infection during early childhood may increase the risk of later coeliac disease, suggests a recent study, adding new data on the role of viral infections in the aetiology of coeliac disease.

Influenza linked to increased hospitalization risk in pregnant women

2 days ago

Seasonal influenza is associated with a heightened risk of hospitalization in pregnant women during all trimesters but not the postpartum period, with the risk varying by influenza type and ethnicity, a study has found.

Original New Drug Application Approvals by US FDA (01- 15 February 2019)

4 days ago

New drug applications approved by US FDA as of 01- 15 February 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

CDI ups mortality risk in IBD patients

5 days ago

Clostridium difficile infection (CDI) is associated with increased mortality risk in patients with inflammatory bowel disease (IBD), based on the results of a meta-analysis involving 10 observational studies with at least moderate quality.

HKU investigators discover EBV variants strongly associated with nasopharyngeal cancer

Dr. Joseph Delano Fule Robles, 12 Feb 2019

A team of investigators from the University of Hong Kong (HKU) identified high-risk Epstein Barr virus (EBV) variants present in 97 percent of nasopharyngeal carcinoma (NPC) cases.

Paediatric vaccination improves patient adherence, reduces paediatric mortality

17 Dec 2018

At the 40th Malaysian Paediatric Association Annual Congress held on 6 September 2018 at the Ipoh Convention Centre, Dr Yong Junina Fadzil discussed the applications of a hexavalent vaccine in optimizing paediatric vaccination schedules. Meanwhile, Dato’ Dr Musa Mohd Nordin shared his insights into the paediatric influenza ‘landscape’ in the region and highlighted the importance of regularly vaccinating paediatric patients.

Influenza prophylaxis to reduce complications in high-risk populations

01 Jul 2018

Influenza is a highly contagious viral disease, which is primarily spread through water droplets containing strains of the virus. Dr Leong Chee Loon shares his insights into the management of influenza in Malaysia, highlighting the importance of improving vaccination coverage in populations at high-risk of influenza-related complications, such as elderly patients and healthcare practitioners.

Paediatric vaccination: An effective measure against vaccine-preventable diseases

01 Mar 2018

At the 13th Asian Congress of Paediatric Nephrology 2017 in conjunction with the 39th Malaysian Paediatric Association Annual Congress, Dr Wanatpreeya Phongsamart spoke on the importance of influenza vaccination in children, highlighting the role of quadrivalent influenza vaccine (QIV) in providing a broader protection against influenza. Meanwhile, Emeritus Professor Somsak Lolekha shared his insights into the effectiveness of a hexavalent vaccine in paediatric immunization, and discussed its role in the Malaysian paediatric immunization schedule.

Viral respiratory infection POCT could reduce unnecessary hospitalization, antibiotics

Roshini Claire Anthony, 09 Oct 2018

The implementation of point-of-care testing (POCT) for viral respiratory infections in emergency departments could reduce unnecessary hospitalizations and antibiotic treatment, according to a study from the UK.

Airway microbiota associated with lung cancer development

Dr. Joseph Delano Fule Robles, 02 Oct 2018

The airway microbiota is recently demonstrated to be associated with lung cancer via up-regulation of the ERK, PI3K and IL-17A signalling pathways, according to data presented at the recent European Respiratory Society (ERS) International Congress 2018.

Short-term azithromycin may reduce ureaplasma infection-related morbidity in preterm infants

Roshini Claire Anthony, 27 Sep 2018

Preterm infants who tested positive for ureaplasma respiratory tract infection had poorer survival over the first year of life, according to a study presented at ERS 2018. However, a 3-day course of prophylactic azithromycin could potentially reduce this morbidity and mortality burden.

Higher rate of cancer, all-cause mortality among teens, young adults with perinatally acquired HIV

Roshini Claire Anthony, 29 Aug 2018

Teenagers and young adults living with perinatally acquired HIV (PaHIV) have a higher risk of developing malignancies and a higher all-cause mortality rate than their non-HIV-infected peers, according to a study from the UK.

CD4/CD8 ratio may predict risk of Kaposi sarcoma, NHL in HIV patients

Pearl Toh, 23 Aug 2018

Restoration of CD4/CD8 ratio on combination antiretroviral therapy (cART) was associated with decreased risk of Kaposi sarcoma (KS) while baseline CD8 count was related to non-Hogkin lymphoma (NHL) risk in people living with HIV (PLHIV) who had achieved viral suppression on cART, according to the COHERE* study presented at the AIDS International Conference (AIC) 2018.

No harms on offspring cognition with peripartum ART

Pearl Toh, 21 Aug 2018

Use of triple antiretroviral therapy (ART) during pregnancy and breastfeeding did not affect the cognitive development and function of the offspring compared with those whose mothers were not exposed to ART, reveals the IMPAACT PROMISE-BF study presented at the IAC 2018.

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