Top Medical News
Roshini Claire Anthony, 2 days ago

Use of the blood infection biomarker procalcitonin as a guide to prescribing antibiotics led to lower antibiotic exposure and side effects, as well as a lower mortality rate in individuals with acute respiratory infections, based on findings of a meta-analysis.

3 days ago
The paediatric dosing of intravenous zanamivir has a safety profile that is consistent with that expected in a population of children hospitalized for severe or progressive influenza, with majority achieving clinical improvement during the treatment course, according to a study.
Jairia Dela Cruz, 3 days ago
Treatment with a ribavirin-free regimen of coformulated glecaprevir plus pibrentasvir appears to yield a high rate of sustained virologic response in hepatitis C virus-infected patients with advanced chronic kidney disease, while having an acceptable safety profile, according to the EXPEDITION-4 trial.
Roshini Claire Anthony, 4 days ago

Patients with acute-on-chronic liver failure (ACLF) who fulfil both APASL* and EASL** criteria have an elevated risk of liver disease-related mortality, according to a retrospective single-centre study conducted in Singapore. The findings also revealed the factors associated with a poorer prognosis.

4 days ago
New drug applications approved by US FDA as of 1 - 15 November 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
6 days ago
Asymptomatic reservoirs appear to be able to transmit large amounts of norovirus (NoV) on their stools, a recent study from Indonesia shows. Thus, this may be a potential source of NoV outbreaks.
12 Nov 2017
In patients infected with Helicobacter pylori, long-term use of proton pump inhibitors is associated with an increased risk of gastric cancer even after treatment for the infection, a recent population-based study has shown.
Special Reports
02 Nov 2017
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia. 
14 Aug 2017
In this edition of MIMS Infectious Disease, we bring you selected updates in the HIV treatment, and also symposium highlights from the relaunch of Tivicay (dolutegravir; GSK, ViiV Healthcare).
12 Jul 2017
DUKORAL – Inactivated Vibrio cholerae O1 serogroup & recombinant cholera toxin B subunit (WC/rCTB) vaccine (oral) – AJ Biologics
01 Mar 2017
At the recent Asia Pacific Alliance for the Control of Influenza (APACI) workshop in Kuala Lumpur, MIMS Doctor had the privilege of having an exclusive interview with eminent paediatric infectious disease specialist, Associate Professor Tawee Chotpitayasunondh. This article captures the highlights from our conversation with him.
Stephen Padilla, 06 Dec 2016
Dengvaxia, a recombinant, live-attenuated dengue vaccine, has the potential to bring down the number of hospitalizations by 13 to 25 percent and be cost-effective in areas of moderate-to-high dengue endemicity, according to a model comparison study.
02 Dec 2016
The Asia Pacific Alliance for the Control of Influenza (APACI) recently organized an influenza workshop in Kuala Lumpur. The workshop saw eminent speakers from seven countries presenting on topics concerning the impact of influenza, vaccination of various populations, current and upcoming treatments for influenza, policy considerations and approaches for pandemic preparedness. Read about highlights from the workshop in this newsletter. 
23 Nov 2016
At the recent Infectious Disease Symposium held on the 5th of August 2016, at Le Meridien Kuala Lumpur, two speakers spoke on the role of macrolides in the management of respiratory tract infections, as well as the importance of antibiotic stewardship in combating microbial resistance.
Conference Reports
Dr Joslyn Ngu, 09 Nov 2017

A set of statistical models running on the Least Absolute Shrinkage and Selection Operator (LASSO) method is used to forecast the incidence of dengue in Singapore and to manage potential outbreaks, reveals an analyst.

Dr Joslyn Ngu, 09 Nov 2017

Several human and mosquito-related factors contribute to the re-emergence of chikungunya in the country, says a medical microbiologist.

Rachel Soon, 21 Aug 2017

Field trials of a biological control program to subdue dengue are showing some promise in reducing the spread of the disease. 

21 Aug 2017

A set of statistical models running on the Least Absolute Shrinkage and Selection Operator (LASSO) method is used to forecast the incidence of dengue in Singapore and to manage potential outbreaks, reveals an analyst.

21 Aug 2017

Several human and mosquito factors contribute to the re-emergence of chikungunya in the country, says a medical microbiologist.

Rachel Soon, 21 Aug 2017

Individuals carrying the dengue virus (DENV) and showing little to no outward symptoms of the disease may play a larger role in dengue fever epidemics than previously expected, says an expert.

Elaine Tan, 14 Aug 2017

Complicated and uncomplicated urinary tract infections (UTIs) in adults and children should be managed by identifying and treating predisposing or underlying risk factors, with antimicrobial treatment, if needed, based on urine culture results and regional antibiotic resistance patterns, according to new guidelines of the Urological Association of Asia (UAA) and Asian Association of UTI and STD (AAUS).

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