Hypothyroidism is a common endocrine disorder where in the thyroid does not make enough thyroid hormone.
Subclinical/mild hypothyroidism refers to the state of slightly increased serum TSH with normal serum FT4 in patients who are usually asymptomatic.
Most common cause of primary hypothyroidism is autoimmune thyroiditis or Hashimoto's disease.
Levothyroxine is the first-line agent for treatment of hypothyroidism.
Roshini Claire Anthony speaks to Dr Adoree Lim, a consultant at the Department of Endocrinology, Singapore General Hospital, on how GPs can help tackle hyper- and hypothyroidism in the primary care setting.
Levothyroxine demonstrates a lowering effect on total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol in patients with subclinical hypothyroidism (SCH), including those with mild SCH, according to a systematic review and meta-analysis.
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A low-carbohydrate diet increases energy expenditure during weight loss maintenance, consistent with the carbohydrate-insulin model, a study has shown. This metabolic effect may contribute to the success of obesity treatment, particularly among those with high insulin secretion.
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