Hyperthyroidism is the overactivity of the thyroid gland resulting in excessive production of thyroid hormones.
Symptoms are of gradual onset.
Earliest signs may be emotional lability and motor hyperactivity; decline in school performance may also be noted.
Causes are autoimmune (Grave's disease), inappropriate stimulation by trophic factors, passive release of preformed thyroid hormone stores in response to infections, trauma, or other offensive factors inside the body, and extra-thyroidal sources.
Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
Cabozantinib is not better than mitoxantrone-prednisone at relieving pain in patients with metastatic castration-resistant prostate cancer (mCRPC) with symptomatic bone metastasis, a recent study suggests.