hodgkin's%20lymphoma
HODGKIN'S LYMPHOMA

Hodgkin's lymphoma is a malignancy that arises from germinal center B cell.

Histologically, there is a presence of multinucleated giant cells in a mixed inflammatory background.

It is also known as Hodgkin's disease, Hodgkin lymphoma or Hodgkin disease.

It commonly affects individuals ages 15-30 years old and those 55 years old and above.

The key morphologic characteristics include presence of Reed-Sternberg cells and lymphocyte-predominant cells.

Differential Diagnosis

  • Non-Hodgkin’s lymphoma (NHL) particularly diffuse large B-cell lymphoma & anaplastic large cell lymphoma
  • Infectious mononucleosis
  • Lymphadenopathy secondary to infection
  • Sarcoidosis
  • Small cell lung cancer
  • Pulmonary tuberculosis
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