Patients with nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) suffer from higher surgical morbidity and posthepatectomy liver failure, according to a new Singapore study.
Nonalcoholic fatty liver disease (NAFLD) is linked to coronary artery calcification and carotid intima-media thickness (IMT) in people without a history of cardiovascular disease, a recent study has shown.
A Singapore study has shown the association of nosocomial spontaneous bacterial peritonitis (N-SBP) with recent antibiotic use, longer hospitalization, more resistant organism and poorer survival among patients with SBP. Moreover, N-SBP and Model for End-stage Liver Disease (MELD) score are predictors of higher mortality in SBP.
Treatment with rifaximin for overt hepatic encephalopathy recurrence in patients on liver transplantation waitlist appears to significantly lessen hospital admissions associated with spontaneous bacterial peritonitis, ascites and variceal bleeding, a recent study has found. Furthermore, it helps reduce requirement for transplant prioritization and prolong time to hospital readmission.
Type 2 diabetes patients with nonalcoholic steatohepatitis (NASH) and advanced fibrosis may fare well with long-term use of metformin, as the drug confers marked benefits for transplant-free survival and helps prevent the development of hepatocellular carcinoma (HCC), according to a recent study.
Measurement of spleen stiffness (SS) may be utilized to assess the risk of a hepatic decompensation and may therefore be used a robust screening tool to identify patients who need closer monitoring, suggests a study. In addition, SS can differentiate between acute and chronic or acute on chronic liver damage.
Statins, depending on types and doses, appear to be associated with an increased risk of developing transaminitis or hypertransaminasemia, with the results of a meta-analysis showing that high-dose atorvastatin, rosuvastatin and lovastatin yield higher risks of liver-function test abnormalities.
In patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), rivaroxaban monotherapy is noninferior to combination treatment with an antiplatelet therapy in terms of cutting the risk of cardiovascular events and mortality, according to data from the AFIRE trial.
Many patients with nonvalvular atrial fibrillation (NVAF) in Thailand use anticoagulants, but the uptake of nonvitamin-K oral anticoagulants remains suboptimal despite showing an upward trend, according to data from the COOL-AF registry presented at the European Society of Cardioloy (ESC) Asia Congress 2019 with APSC and AFC.
Monotherapy with tocilizumab (TCZ) shows good tolerability profile and results in remission in most patients with polymyalgia rheumatica (PMR) despite the absence of glucocorticoids, according to the 2-year results of a single-centre, open‐label pilot study.