Surgical resection (SR) as a first-line treatment for small perivascular hepatocellular carcinoma (HCC) provides better long-term tumour control than radiofrequency ablation (RFA), a recent study has shown.
The addition of bezafibrate to ursodeoxycholic acid improves biochemical responses over ursodeoxycholic acid alone in patients with primary biliary cholangitis, according to results of the BEZURSO* trial.
Increased levels of plasma proneurotensin (pro-NT) can predict the presence or severity of nonalcoholic fatty liver disease (NAFLD) in adults, a recent study has shown. Moreover, NT may specifically promote hepatic fat accumulation in dysmetabolic individuals through mechanisms possibly related to increased insulin resistance.
There appears to be a link between use of proton pump inhibitors (PPIs) and liver cancer, although more work is needed to determine whether this association is causal or reflects residual confounding or reverse causation, according to a study.
Persons with blood bilirubin levels in the higher range of normal have lower rates of heart failure, myocardial infarction and stroke in patients with or without HIV infection, reveals a new large-scale study.
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
A treatment regimen combining daratumumab plus bortezomib, melphalan and prednisone markedly extends progression-free survival in patients with multiple myeloma, inducing deep responses and demonstrating acceptable tolerability regardless of baseline renal function, according to the results of the phase III ALCYONE study.
Segmentectomy and lobectomy confer similar overall survival (OS) and lung cancer-specific survival (LCSS) among patients with primary nonsmall cell lung cancer (NSCLC) of ≤20 mm without lymph node or distant metastasis, a recent study has shown.