Increased levels of plasma proneurotensin (pro-NT) can predict the presence or severity of nonalcoholic fatty liver disease (NAFLD) in adults, a recent study has shown. Moreover, NT may specifically promote hepatic fat accumulation in dysmetabolic individuals through mechanisms possibly related to increased insulin resistance.
Persons with blood bilirubin levels in the higher range of normal have lower rates of heart failure, myocardial infarction and stroke in patients with or without HIV infection, reveals a new large-scale study.
Treatment with the synthetic thyroid hormone (TH) levothyroxine can decrease intrahepatic lipid content (IHLC) in patients with nonalchoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D), especially in older patients, a recent study found.
The 2018 EHRA* practical guide on non–vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) walks clinicians through 20 topics of clinical scenarios, including stroke management, NOAC use in conditions other than AF, and when to measure plasma levels. [Eur Heart J 2018; doi.org/10.1093/eurheartj/ehy136]
A multispecialty team of healthcare professionals in University of Malaya (UM) has successfully carried out their first living donor liver transplantation last year and since then performed three living donor liver transplants over the past year.
Patients with locally advanced hepatocellular carcinoma (HCC) from the Asia Pacific region had comparable overall survival (OS) regardless of whether they were treated with selective internal radiation therapy (SIRT) or sorafenib. However, SIRT appeared to be more tolerable than sorafenib, according to results of the phase III SIRveNIB* trial.
The addition of low-dose cisplatin plus fluorouracil hepatic arterial infusion chemotherapy to sorafenib provides no additional survival benefit over sorafenib alone for patients with advanced, unresectable hepatocellular carcinoma, a recent randomized phase III study has shown.
Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.