Patients with nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) suffer from higher surgical morbidity and posthepatectomy liver failure, according to a new Singapore study.
A Singapore study has shown the association of nosocomial spontaneous bacterial peritonitis (N-SBP) with recent antibiotic use, longer hospitalization, more resistant organism and poorer survival among patients with SBP. Moreover, N-SBP and Model for End-stage Liver Disease (MELD) score are predictors of higher mortality in SBP.
Treatment with rifaximin for overt hepatic encephalopathy recurrence in patients on liver transplantation waitlist appears to significantly lessen hospital admissions associated with spontaneous bacterial peritonitis, ascites and variceal bleeding, a recent study has found. Furthermore, it helps reduce requirement for transplant prioritization and prolong time to hospital readmission.
Type 2 diabetes patients with nonalcoholic steatohepatitis (NASH) and advanced fibrosis may fare well with long-term use of metformin, as the drug confers marked benefits for transplant-free survival and helps prevent the development of hepatocellular carcinoma (HCC), according to a recent study.
Measurement of spleen stiffness (SS) may be utilized to assess the risk of a hepatic decompensation and may therefore be used a robust screening tool to identify patients who need closer monitoring, suggests a study. In addition, SS can differentiate between acute and chronic or acute on chronic liver damage.
Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.
Treatment with the direct-acting antiviral (DAA) combination of glecaprevir and pibrentasvir led to encouraging sustained virological response (SVR) among individuals with hepatitis C virus (HCV) infection, results of two real-world studies presented at the International Liver Congress™ (ILC 2019) showed.
The trend in liver disease-related mortality in individuals with HIV has changed, with a reduction in the incidence of viral hepatitis-related deaths and an increase in non-alcoholic fatty liver disease (NAFLD)-related deaths, according to a study presented at the International Liver Congress™ (ILC 2019).
Long-term treatment with β blockers improves decompensation-free survival in patients with compensated cirrhosis and clinically significant portal hypertension (CSPH), according to the PREDESCI* study, which heralds a new youth for β blockers conventionally used for treating primary hypertension.
Patients with non-alcoholic steatohepatitis (NASH) may benefit from treatment with a 25 mg/day dose of obeticholic acid, according to the interim analysis of the phase III REGENERATE* study presented at the International Liver Congress™ (ILC 2019).
Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.