The consumption of fructose from fruit juice and sugar sweetened beverages (SSBs), but not from fruit, is associated with higher intrahepatic lipid (IHL) content, according to data from a cross-sectional study presented at EASD 2021.
Recent research has found that mutations in the human EZH2 and CCND1 genes may be potential novel biomarkers for liver cancer. The tumour mutation burden (TMB) also appears to be an important prognostic factor and affects patient survival.
Most cases of paediatric acute liver failure (PALF) in Singapore are still of indeterminate aetiology, according to a recent single-centre study. Given the poor survival prospects of PALF, timely liver transplantation (LT) is critical.
Hepatocellular carcinoma (HCC) in Singapore has changed markedly throughout the last decade, with patients being diagnosed at an increasingly older age and cryptogenic cirrhosis/nonalcoholic steatohepatitis (NASH) becoming a more important aetiology, according to a recent study.
Circulating tumour cells are more frequently detected in peripheral blood samples of patients with more advanced than early-stage hepatocellular carcinoma (HCC), according to a study presented at the recently concluded Asian Pacific Digestive Week 2021.
Lenvatinib confers better clinical outcomes than sorafenib in patients with unresectable hepatocellular carcinoma (uHCC) even when their liver function deteriorates to Child-Pugh B after initiation of treatment, according to a post hoc analysis of the REFLECT study.
Adding the VEGFR*-2 antagonist ramucirumab to paclitaxel extends survival of patients with advanced gastric/GEJ** adenocarcinoma compared with paclitaxel alone, regardless of liver metastasis status, according to a post hoc analysis of the RAINBOW*** trial presented at the ESMO GI 2021 Congress.
Though skin cancer incidence is low, liver transplant recipients may still benefit from long-term dermatological surveillance to help monitor malignancies and infections, according to a recent Singapore study.
Universal access to direct-acting antivirals (DAAs) may have led to the low prevalence of hepatitis C viraemia among people living with HIV (PLHIV) in The Netherlands, according to a study presented at IAS 2021.