Neither rifaximin nor norfloxacin, both poorly absorbable antibiotics, significantly reduces hepatic venous pressure gradient in patients with portal hypertension and cirrhosis, a recent study has found.
Epeleuton, a second‐generation synthetic n‐3 fatty acid derivative of eicosapentaenoic acid, falls short of improving alanine aminotransferase or liver stiffness in patients with nonalcoholic fatty liver disease (NAFLD), according to a study. However, it has potential for cardiovascular risk reduction by simultaneously targeting hypertriglyceridemia, hyperglycaemia, and systemic inflammation.
Use of aldafermin, an engineered analogue of FGF19, appears beneficial in the treatment of patients with nonalcoholic steatohepatitis (NASH), reducing liver fat and markers of disease progression without any adverse side effects, according to the results of a phase II trial.
Treatment with besifovir dipivoxil maleate (BSV) is effective and safe for long-term use in treatment-naïve and tenofovir disoproxil fumarate (TDF)-experienced patients with chronic hepatitis B (CHB), results of a phase III trial have shown.
Statin use demonstrates a protective effect against hepatocellular carcinoma (HCC), while hypertension confers an increased risk, in patients with nonalcoholic fatty liver disease (NAFLD), a study has found.
The low rate of retransplantation in patients with recurring autoimmune hepatitis (AIH) is partly to blame for the greater post-transplant mortality in this population compared with other autoimmune liver disease, suggests a recent study.
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
For individuals with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.