Hepatology

Top Medical News
Audrey Abella, 4 days ago
Long-term use of ipragliflozin improves obesity, glycaemic control, and hepatic outcomes in patients with type 2 diabetes (T2D) who developed nonalcoholic fatty liver disease (NAFLD), a study shows.
30 Jun 2020
Healthy patients with significant fibrosis related to nonalcoholic fatty liver disease (NAFLD) are at a higher risk of developing type 2 diabetes mellitus (T2DM) and arterial hypertension (AHT), a recent study has shown.
26 Jun 2020
Bariatric surgery may lead to the resolution of nonalcoholic steatohepatitis (NASH) with a sustained reduction in fibrosis over 5 years, as shown in a study.
Stephen Padilla, 25 Jun 2020
A recent study involving Chinese patients with nonalcoholic fatty liver disease (NAFLD) suggests that positive antihepatitis B core antibody (anti-HBc) is linked to cirrhosis and possibly hepatocellular carcinoma (HCC) and cirrhotic complications.
Tristan Manalac, 25 Jun 2020
There is a need to develop a better predictive tool for detecting nonobese patients with nonalcoholic fatty liver disease (NAFLD) at risk of advanced fibrosis, according to a new Singapore study.
25 Jun 2020
In patients with co-infection of hepatitis B (HBV) and hepatitis C (HCV) virus, low levels of hepatitis B surface antigen (HBsAg) prior to treatment with direct-acting antivirals (DAA) appear to lead to better HBV seroclearance, a recent study has found.
23 Jun 2020
Obeticholic acid (OCA) reduces serum concentrations of alkaline phosphatase (ALP) in patients with primary sclerosing cholangitis, a new study has found.
Special Reports
Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
Dr Raghav Sundar, 09 Sep 2019

Overall survival (OS) is currently the primary criteria in assessing the efficacy of a cancer treatment. Dr Raghav Sundar, a consultant medical oncologist at the National University Hospital, Singapore, details the crucial role played by tumour response in evaluating treatment efficacy, with a focus on the multiple kinase inhibitor lenvatinib in the treatment of hepatocellular carcinoma (HCC).  

Conference Reports
Roshini Claire Anthony, 10 May 2019

Treatment with the direct-acting antiviral (DAA) combination of glecaprevir and pibrentasvir led to encouraging sustained virological response (SVR) among individuals with hepatitis C virus (HCV) infection, results of two real-world studies presented at the International Liver Congress (ILC 2019) showed.

Roshini Claire Anthony, 07 May 2019

The trend in liver disease-related mortality in individuals with HIV has changed, with a reduction in the incidence of viral hepatitis-related deaths and an increase in non-alcoholic fatty liver disease (NAFLD)-related deaths, according to a study presented at the International Liver Congress (ILC 2019).

Roshini Claire Anthony, 02 May 2019

Patients with non-alcoholic steatohepatitis (NASH) may benefit from treatment with a 25 mg/day dose of obeticholic acid, according to the interim analysis of the phase III REGENERATE* study presented at the International Liver Congress (ILC 2019).

Audrey Abella, 30 Apr 2019
Nonalcoholic fatty liver disease (NAFLD, or steatosis) was prevalent in a substantial number of young adults, suggesting an imminent public health crisis if left undiagnosed and untreated, according to data from a large UK trial presented at ILC 2019.
Roshini Claire Anthony, 29 Apr 2019

Adults with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) who progress to advanced liver disease have an elevated risk of mortality compared with non-progressors, according to two separate studies conducted in Germany and France and presented at the International Liver Congress (ILC 2019).

Audrey Abella, 25 Apr 2019
Patients with chronic hepatitis B virus (HBV) infection treated with the nucleot(s)ide analogue tenofovir disoproxil fumarate (TDF) had a lower risk of hepatocellular carcinoma (HCC) than those treated with entecavir, according to data from a large observational study presented at ILC 2019.
Christina Lau, 22 Feb 2018

Cabozantinib, an oral inhibitor of multiple tyrosine kinases, significantly improves overall survival (OS) and progression-free survival (PFS) in patients with advanced hepatocellular carcinoma (HCC) whose disease progressed following sorafenib or other systemic therapies.

CME Modules
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