Treatment Guideline Chart

Hepatitis B is transmitted through perinatal, percutaneous, sexual, and close person-to-person contact, ie by open cuts and sores.

Human hepatitis B virus belongs to the family of Hepadnaviridae of small, enveloped, primarily hepatotropic DNA viruses. The virus replicates in the host and assembles exclusively in the hepatocytes and virions are released non-cytopathically through the cellular secretory pathway.

Chronic hepatitis B is defined as a chronic necroinflammatory liver disease due to persistent hepatitis B virus infection.

Hepatitis D infection is found only in patients with hepatitis B as it requires the hepatitis B outer coat. It is transmitted through sexual and percutaneous (especially IV drug use) routes.

Hepatitis B and D both have an incubation period of 30-180 days.

Hepatitis%20b Diagnosis

Differential Diagnosis

  • Hepatitis A, D, E: Specific serologic testing identifies the different types of hepatitis
  • Viral diseases: Yellow fever, Epstein-Barr virus, cytomegalovirus, HIV, rubella, rubeola, coxsackie B, adenovirus, herpes simplex, herpes zoster
  • Nonviral diseases: Leptospirosis, toxoplasmosis, alcoholic hepatitis, autoimmune hepatitis, drug-induced hepatitis/liver injury, toxic hepatitis, cirrhosis, HCC, Wilson disease
Editor's Recommendations
Special Reports