Growth hormone deficiency is a congenital or an acquired growth hormone axis disruption in the higher brain, hypothalamus or pituitary which results in short stature.
It may occur at any age.
Short stature is often the only feature present in patients with growth hormone deficiency and other causes of subnormal growth rate.
Etiology may be congenital conditions (eg defective pituitary development that leads to pituitary aplasia, empty sella, encephalocele, midline defects) or acquired conditions (eg tumors of the hypothalamic-pituitary region, cranial irradiation, infiltrative disease).
Growth hormone (GH) replacement therapy increased left ventricular (LV) mass and improved metabolic parameters in prepubertal children with growth hormone deficiency (GHD), according to a study from Spain.
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Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
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Due to varying analyses and reporting methods, fever rates in studies substantially differ. As such, there is a need for standardized fever reporting to allow comparisons between studies, according to a recent investigation.