Treatment Guideline Chart
Gout is a condition that resulted from deposition of monosodium urate crystals in various tissues (eg joints, connective tissue, kidney).
The patient experiences acute and chronic arthritis, soft tissue inflammation, tophus formation, gouty nephropathy and nephrolithiasis.
Primary hyperuricemia occurs when uric acid saturation arises without coexisting diseases or drugs that alter uric acid production or excretion, while secondary hyperuricemia is a condition where excessive uric acid production or diminished renal clearance occurs as a result of a disease, drug, dietary product or toxin. 

Gout References

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  3. Khanna D, Khanna PP, Fitzgerald JD, et al; American College of Rheumatology. 2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis. Arthritis Care Res (Hoboken). 2012 Oct;64(10):1447-1461. http://www.ncbi.nlm.nih.gov/pubmed/?term=Khanna++D%2C+Khanna++PP%2C+Fitzgerald++JD%2C+et++al%09%222012+American+College+of+Rheumatology+guidelines+for+management+of+gout.+Part++2%3A+therapy+and+antiinflamatory++prophylaxis+of++acute+gouty++arthritis%22. PMID: 23024029
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  12. National Institute for Health and Care Excellence (NICE). Pegloticase for treating severe chronic tophaceous gout. NICE. http://publications.nice.org.uk/pegloticase-for-treating-severe-debilitating-chronic-tophaceous-gout-ta291/about-this-guidance. Jun 2013.
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  24. Editorial. Hitting the target in gout. The Lancet Rheumatology. 2020 Jan;2(1). https://doi.org/10.1016/S2665-9913(19)30131-6.
  25. Li Q, Li X, Wang J, et al. Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements. BMJ Open. 2019 Aug;9(8):e026677. doi: 10.1136/bmjopen-2018-026677. Accessed 28 Feb 2020. PMID: 31446403
  26. FitzGerald JD, Dalbeth N, Mikuls T, et al. 2020 American College of Rheumatology guideline for the management of gout. Arthritis Care Res (Hoboken). 2020 Jun;72(6):744-760. doi: 10.1002/acr.24180. Accessed 22 May 2020. PMID: 32391934
  27. Gaffo AL. Treatment of gout flares. UpToDate. https://www.uptodate.com. 03 Feb 2022.
  28. Golenbiewski J, Keenan RT. Moving the needle: improving the care of the gout patient. Rheumatol Ther. 2019 Jun;6(2):179-193. doi: 10.1007/s40744-019-0147-5. PMID: 30826988
  29. Pascart T, Latourte A, Flipo RM, et al. 2020 Recommendations from the French Society of Rheumatology for the management of gout: urate-lowering therapy. Joint Bone Spine. 2020 Oct;87(5):395-404. doi: 10.1016/j.jbspin.2020.05.002. Accessed 10 Mar 2022. PMID: 32422338
  30. Perez-Ruiz F. Pharmacologic urate-lowering therapy and treatment of tophi in patients with gout. UpToDate. https://www.uptodate.com. 16 Dec 2020.
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  33. Yip RML, Cheung TT, So H, et al. The Hong Kong Society of Rheumatology consensus recommendations for the management of gout. Clin Rheumatol. 2023 Apr 4. doi: 10.1007/s10067-023-06578-9. PMID: 37014501
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