gout
GOUT
Gout is a condition that resulted from deposition of monosodium urate crystals in various tissues (eg joints, connective tissue, kidney).
The patient experiences acute and chronic arthritis, soft tissue inflammation, tophus formation, gouty nephropathy and nephrolithiasis.
Primary hyperuricemia occurs when uric acid saturation arises without coexisting diseases or drugs that alter uric acid production or excretion, while secondary hyperuricemia is a condition where excessive uric acid production or diminished renal clearance occurs as a result of a disease, drug, dietary product or toxin. 

Differential Diagnosis

  • Septic arthritis
    • It is important to rule out septic arthritis because if not diagnosed early, this can lead to rapid joint destruction associated with significant morbidity and mortality
    • Even if gout has already been confirmed with presence of monosodium urate crystals, one should still check for septic arthritis because these inflammatory conditions may co-exist
  • Rheumatoid arthritis
  • Palindromic rheumatism
  • Reactive arthritis
  • Trauma
  • Pseudogout
  • Acute rheumatic fever
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Rheumatology digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
05 Jun 2018
Men with systemic lupus erythematosus (SLE) are more likely to develop coronary artery calcifications (CAC) than age- and sex-matched controls, a recent study has shown. Such risk among patients with SLE is associated with older age, increasing chronic damage and cumulative dose of corticosteroids.