gout
GOUT
Gout is a condition that resulted from deposition of monosodium urate crystals in various tissues (eg joints, connective tissue, kidney).
The patient experiences acute and chronic arthritis, soft tissue inflammation, tophus formation, gouty nephropathy and nephrolithiasis.
Primary hyperuricemia is called when uric acid saturation arises without coexisting diseases or drugs that alter uric acid production and excretion.
While in secondary hyperuricemia there is an excessive uric acid production or diminished renal clearance that occurs as a result of a disease, drug, dietary product or toxin.

Differential Diagnosis

  • Septic arthritis
    • It is important to rule out septic arthritis because if not diagnosed early, this can lead to rapid joint destruction associated with significant morbidity & mortality
    • Even if gout has already been confirmed with presence of MSU crystals, one should still check for septic arthritis because these inflammatory conditions may co-exist
  • Rheumatoid arthritis
  • Palindromic rheumatism
  • Reactive arthritis
  • Trauma
  • Pseudogout
  • Acute rheumatic fever
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Rheumatology digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
07 Jun 2018
Age, weight, oral corticosteroid use and strenuous exercise at age 18 years appear to be useful in predicting the 5-year risk of height loss of at least 1 inch in postmenopausal women, according to a study.