Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first recognition during pregnancy.
Hyperglycemia in pregnancy may be suggested by the presence of glycosuria, a fetus that is large for date, or polyhydramnios.
Overt diabetes mellitus may be found in women presenting with risk factors for type 2 diabetes during the first prenatal visit (before 13 weeks of gestation).
A lifestyle intervention combining dietary and physical activity counselling initiated during early pregnancy does not appear to effectively improve dietary intake, physical activity, or obstetric and perinatal outcomes in pregnant women at high risk of gestational diabetes mellitus, according to data from the RADIEL trial.
The combination of maternal pregestational diabetes mellitus plus severe obesity is associated with a heightened risk of several psychiatric and mild neurodevelopmental disorders in offspring compared with either obesity or diabetes alone, a study suggests.
High levels of physical activity during pregnancy, especially moderate-intensity and household/caregiving activities, may lower the risk of gestational diabetes mellitus, as shown in a study from Vietnam.
A postnatal lifestyle intervention programme (PAIGE) for overweight women with previous gestational diabetes mellitus (GDM) leads to significantly greater weight loss compared with usual care at 6 months, a recent study has shown.
Women with pre-eclampsia or gestational hypertension during their first pregnancy had an increased risk of developing chronic hypertension, type 2 diabetes (T2D), and hypercholesterolaemia than those who were normotensive during pregnancy, according to a study. The risk persisted for several decades later, signalling these hypertensive disorders of pregnancy (HDP) as red flags for cardiovascular (CV) health for life.
Elevated levels of the free thyroid hormone T3 (fT3) and a higher fT3/fT4 ratio in early pregnancy may point to a greater risk of developing gestational diabetes (GDM), according to a recent US-based study.
Women with gestational diabetes (GDM) or hypertensive disorders of pregnancy (HDP) were threefold more likely than those without these conditions to develop abnormal glucose metabolism or high blood pressure (BP), respectively after delivery, according to the GUSTO* study.
Women who breastfed their infants for a longer duration appeared to have a lower risk of diabetes compared with women who did not breastfeed, according to an observational study spanning three decades.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.