Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first recognition during pregnancy.
Hyperglycemia in pregnancy may be suggested by the presence of glycosuria, a fetus that is large for date, or polyhydramnios.
Overt diabetes mellitus may be found in women presenting with risk factors for type 2 diabetes during the first prenatal visit (before 13 weeks of gestation).
Metformin continues to protect high-risk individuals from developing type 2 diabetes (T2D) over 15 years, especially among those with higher glycaemic status at baseline and women reporting a history of gestational diabetes mellitus (GDM), according to long-term results from DPP/DPPOS*.
Eating vegetable and protein before carbohydrate attenuated postprandial glucose response in healthy Asian adults, according to the PATTERN* study, suggesting that behavioural change in eating sequence may be a potential strategy for modulating glycaemic response.
The cardiovascular (CV) benefits of the SGLT2* inhibitor dapagliflozin extend across a broad spectrum of patients with type 2 diabetes (T2D) and high CV risk, in particular those with heart failure with reduced ejection fraction (HFrEF), reports a subanalysis of the DECLARE-TIMI 58 trial presented at ACC.19 Annual Scientific Session.
A lifestyle intervention combining dietary and physical activity counselling initiated during early pregnancy does not appear to effectively improve dietary intake, physical activity, or obstetric and perinatal outcomes in pregnant women at high risk of gestational diabetes mellitus, according to data from the RADIEL trial.
The combination of maternal pregestational diabetes mellitus plus severe obesity is associated with a heightened risk of several psychiatric and mild neurodevelopmental disorders in offspring compared with either obesity or diabetes alone, a study suggests.
High levels of physical activity during pregnancy, especially moderate-intensity and household/caregiving activities, may lower the risk of gestational diabetes mellitus, as shown in a study from Vietnam.
Empagliflozin treatment in patients with type 2 diabetes mellitus exerts beneficial effects on cardiovascular (CV) risk factors, including blood pressure and uric acid, according to a systematic review and meta-analysis.