Transabdominal interferential electrical stimulation induces bowel symptom improvements in chronically constipated women, and the effects may be sustained 3 months after therapy, according to the results of a trial.
A 7-day course of vonoprazan and low-dose amoxicillin dual (VA-dual) therapy proves useful in the first-line treatment of Helicobacter pylori infection, especially in regions with high clarithromycin resistance, yielding an acceptable eradication efficacy that is similar to that achieved with vonoprazan-based triple (VAC-triple) therapy, according to the results of an open-label trial.
The combination of pinaverium bromide 100 mg plus simethicone 300 mg is effective in the treatment of bloating (PB+S) and abdominal pain in patients with active irritable bowel syndrome (IBS), a study has shown. The effect of combined therapy on the frequency of stool consistency was significant in IBS with constipation (C) and mixed-type (M) IBS.
Proton pump inhibitors (PPIs) may increase susceptibility to osteoporotic fractures in elderly women as compared with histamine-2 receptor antagonists (H2RAs), especially those who have used PPIs for at least a year, a recent study in Korea has found.
Use of the bile acid sequestrant IW-3718 as an adjunct to proton pump inhibitor (PPI) therapy is well tolerated and reduces heartburn and regurgitation symptoms in patients with refractory gastro-oesophageal reflux disease (GERD), according to the results of a trial.
Real-world data from the PCORnet* Bariatric Study suggest that Roux-en-Y gastric bypass (RYGB) may be preferable to sleeve gastrectomy (SG) in inducing and maintaining type 2 diabetes (T2DM) remission.
Exposure to nitroimidazole appears to mitigate the efficacy of nitroimidazole-based triple regimen, but not quadruple therapy, in patients with Helicobacter pylori infection, results of a study have shown.
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Among patients with nonvalvular atrial fibrillation (AF), treatment with apixaban was associated with a lower rate of ischaemic stroke, systemic embolism, and major bleeding compared with rivaroxaban, according to a large study assessing patients in routine care.