A technology based on analysis of images taken using a smartphone provides acceptable estimates of total serum bilirubin levels in newborn infants, with an accuracy that does not differ from that of transcutaneous bilirubin measurement, according to a US study.
Treatment with a ribavirin-free regimen of coformulated glecaprevir plus pibrentasvir appears to yield a high rate of sustained virologic response in hepatitis C virus-infected patients with advanced chronic kidney disease, while having an acceptable safety profile, according to the EXPEDITION-4 trial.
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
Close to 50 percent of diabetic patients with dysphagia are found to have some type of an oesophageal motility disorder, according to a new study. Moreover, diabetic retinopathy and insulin use among diabetic patients are risk factors for oesophageal motor abnormalities.
New drug applications approved by US FDA as of 1 - 15 November 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
The apoptosis signal-regulating kinase 1 (ASK1) inhibitor selonsertib appears to have favourable effects on liver fibrosis in patients with nonalcoholic steatohepatitis and stage II to III fibrosis, according to the results of a phase II exploratory trial.
A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated.
Vitamin K antagonist (VKA) may increase the risk of minor bleeding in cirrhotic patients receiving anticoagulants for portal vein thrombosis (PVT), according to a study. However, this risk is compensated for by the ability of VKA to increase portal hypertension-related, event-free and transplantation-free survival of patients with PVT recanalization.
New endoscopic technologies have improved outcomes for patients with upper gastrointestinal bleeding (UGIB), according to Professor James Lau from the Chinese University of Hong Kong, who reviewed current treatment practices and latest advances at the Asian Pacific Digestive Week (APDW) 2017 held recently in Hong Kong.
The efficacy of endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) is comparable with that of laparoscopic gastrojejunostomy (Lap-GJ), but the former has more complex patients with gastric outlet obstruction (GOO), reports a recent study. Furthermore, the EUS-GJ group has significantly lower adverse events.
Children with autism spectrum disorders (ASD) appear to have significantly altered gut mucosal mitochondrial function compared with controls and other children with nonspecific gastrointestinal symptoms, a recent study shows.
Serum albumin appears to be useful in predicting early mortality in Asian patients with severe hypoxic hepatitis, with low baseline levels entailing a fivefold increase in risk of death, as shown in a Singapore study.