Adding high-dose vitamin D3 to standard chemotherapy for metastatic colorectal cancer (mCRC) may confer potential benefit to previously untreated patients in terms of progression-free survival (PFS) compared with supplemental standard-dose vitamin D3, suggests the phase II SUNSHINE* study.
A wearable tracker, combined with action-planning, successfully improves moderate-to-vigorous physical activity (MVPA) levels in survivors of colorectal and endometrial cancers, according to a new study.
A recent study by investigators from Hong Kong showed that poor sleep quality and longer sleep onset latency are associated with an increased risk of peptic ulcer disease (PUD) recurrence. Depression is also shown to be associated with subsequent incidence of PUD.
Gastric emptying occurs faster with elemental liquid diets than standard semisolid diets in bedridden percutaneous endoscopic gastronomy (PEG)-fed patients, results from two studies have shown. In addition, aspiration pneumonia may be prevented or reduced with elemental liquid diet tube feedings.
About one-fifth of all prescriptions for inflammatory bowel disease appear to be off-label, and these are more frequently written for patients with ulcerative colitis as opposed to Crohn’s disease, according to a recent study from the Netherlands.
The use of glecaprevir plus pibrentasvir appears to be safe and highly effective in the treatment of chronic hepatitis C virus (HCV) infection genotypes 1–3 in patients with severe renal impairment, including those undergoing haemodialysis, as shown in a recent study from Japan.
The novel potassium‐competitive acid blocker tegoprazan at either 50 or 100 mg is noninferior to esomeprazole, a proton pump inhibitor, in the treatment of erosive oesophagitis, with similar healing rates and adverse event incidences, according to the results of a phase III trial conducted in South Korea.
A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.
A study by the Chinese University of Hong Kong (CUHK) has recently shown that low-dose imipramine, a tricyclic antidepressant (TCA), is efficacious for patients with functional dyspepsia not responsive to standard treatment with proton pump inhibitors (PPIs) or prokinetics.
A contraceptive vaginal system (Annovera) releasing a combination of segesterone acetate and ethinyl estradiol (SA/EE) effectively inhibits ovulation up to a year even at low systemic levels of SA, reports a review study presented at ENDO 2019.
Men with advanced prostate cancer who have pre-existing cardiovascular disease (CVD) may have an elevated mortality risk after treatment with abiraterone acetate compared with men who do not have CVD, according to a study presented at AACR 2019.