Paediatric-onset inflammatory bowel disease (IBD) carries a doubled risk of developing cancer later in life, with skin, lymphoid, and gastrointestinal tumours of a particular concern, a study has found. The risk is higher in males and independent of IBD subtype and medical treatment.
Three years of adjuvant imatinib treatment is superior in efficacy vs 1-year use in patients with gastrointestinal stromal tumours (GIST) at high risk of recurrence post-surgery, according to the secondary analysis of the SSGXVIII/AIO* trial.
A recent study involving Chinese patients with nonalcoholic fatty liver disease (NAFLD) suggests that positive antihepatitis B core antibody (anti-HBc) is linked to cirrhosis and possibly hepatocellular carcinoma (HCC) and cirrhotic complications.
Gastroesophageal reflux disease (GERD) is a condition which develops when reflux of stomach contents causes troublesome symptoms and/or complications.1 Audrey Abella speaks with Dr Tan Chi Chiu, gastroenterologist and senior consultant, Gastroenterology & Medicine International at Gleneagles Medical Centre, Singapore, to discuss how GERD can be addressed in the primary care setting.
The anti-PD-1 inhibitor camrelizumab demonstrated superior efficacy over chemotherapy (CT) and a tolerable safety profile for advanced/metastatic oesophageal squamous cell carcinoma (OSCC) in Chinese patients, the ESCORT* trial suggests.
Patients with coronavirus disease 2019 (COVID-19) have significant gut dysbiosis that persists even after viral clearance and resolution of respiratory symptoms, according to a metagenomic study by the Chinese University of Hong Kong (CUHK). These findings have led to the development of a probiotic supplement expected to be available in a few months.
A once-daily maintenance dose of vonoprazan 10 mg or 20 mg may be a suitable substitute to lansoprazole in reducing the risk of erosive oesophagitis (EE) recurrence, according to a phase III noninferiority study presented at DDW 2020.
Use of adalimumab or infliximab in biologic-naïve patients with inflammatory bowel disease (IBD) delivers comparable rates of corticosteroid-free remission, as shown by a study presented at the Advances in Inflammatory Bowel Disease (AIBD) Conference 2019.