High-dose esomeprazole in combination with aspirin can moderately reduce the risk of developing high-grade dysplasia or oesophageal cancer or delay death from any cause in patients with Barrett’s oesophagus (BE).
The addition of bezafibrate to ursodeoxycholic acid improves biochemical responses over ursodeoxycholic acid alone in patients with primary biliary cholangitis, according to results of the BEZURSO* trial.
There is an increasing number of studies that shed light on the importance of our gut microbiota. Probiotics are live microorganisms that confer health benefits on the host when administered in adequate amounts. With new data emerging about their proposed benefits in maintaining intestinal health, probiotics continue to gain popularity amongst consumers.
Increased levels of plasma proneurotensin (pro-NT) can predict the presence or severity of nonalcoholic fatty liver disease (NAFLD) in adults, a recent study has shown. Moreover, NT may specifically promote hepatic fat accumulation in dysmetabolic individuals through mechanisms possibly related to increased insulin resistance.
The common antimicrobial agent, triclosan, has been implicated in colonic inflammation and the disease development of colitis and colitis-associated colon cancer, reveals a study appearing in Science Translational Medicine. [doi:10.1126/scitranslmed.aan4116]
Long-term proton-pump inhibitor (PPI) therapy was associated with an increased pneumonia risk among older adults, putting to rest the controversies about the validity of previously reported short-term harms of PPIs, according to a large, longitudinal analysis of electronic medical records.
Breastfed infants supplemented with Bifidobacterium longum subsp. infantis EVC001 were found to have significantly lower quantity and diversity of antimicrobial resistance genes (ARGs) compared to those breastfed alone, a new study shows.
The likelihood of restarting treatment with direct oral anticoagulants (DOACs) following gastrointestinal bleeding (GIB) appears to be low among older patients who require blood and intensive care, a study has shown. Furthermore, a history of venous thromboembolism and thienopyridine use are risk factors for subsequent thromboembolism and GIB, respectively.