Among inflammatory bowel disease (IBD) patients with a current or prior malignancy, treatment with vedolizumab or antitumour necrosis factor (anti-TNF) does not bear an increased hazard of developing new or recurrent cancer, as shown in a study.
Brown rice-based and wheat-based diets improve bowel movement and total colon transit time among women with functional constipation, finds a recent Korea study. Diets reliant on white rice, on the other hand, show no such effect.
Individuals who had undergone liver transplantation (LT) for sarcoidosis have lower graft and patient survival than those with primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC), a study has found. More than six in 10 patients have survived 5 years following transplantation, which suggests the acceptability of LT in this population.
An academic, primary care clinic has significantly and sustainably reduced the inappropriate use of proton pump inhibitors (PPI) to 30 percent from the baseline rates of 80 percent, surpassing its goal within 12 months, a recent study has shown.
N-acetylcysteine provides a protective effect on chemotherapy-induced neuropathy by reducing its incidence and delaying its occurrence in patients with gastric or colorectal cancers, a study has shown.
Thiopurine appears beneficial for long-term treatment of patients with ulcerative colitis (UC) but not for those with Crohn’s disease (CD) especially where there is perianal involvement, a study has found.
Reductions in liver fat and adipose tissue volumes were sustained in patients with type 2 diabetes (T2D) with the addition of the SGLT-2* inhibitor dapagliflozin (DAPA) and the DPP-4** inhibitor saxagliptin (SAXA) to metformin (MET), compared with a regimen comprising glimepiride (GLIM)+MET, according to the extension period results of a phase IIIb trial.