Proton pump inhibitors (PPIs) may increase susceptibility to osteoporotic fractures in elderly women as compared with histamine-2 receptor antagonists (H2RAs), especially those who have used PPIs for at least a year, a recent study in Korea has found.
Use of the bile acid sequestrant IW-3718 as an adjunct to proton pump inhibitor (PPI) therapy is well tolerated and reduces heartburn and regurgitation symptoms in patients with refractory gastro-oesophageal reflux disease (GERD), according to the results of a trial.
Exposure to nitroimidazole appears to mitigate the efficacy of nitroimidazole-based triple regimen, but not quadruple therapy, in patients with Helicobacter pylori infection, results of a study have shown.
Faecal microbiota transplantation (FMT) may be performed in children and young adults to treat Clostridium difficile infection (CDI), with a study showing that the procedure is safe and effective and may be considered earlier in the disease course.
Earlier normalization of serum alanine aminotransferase (ALT) levels in patients with chronic hepatitis B (CHB) who initiated treatment with entecavir or tenofovir correlates with a proportionally lower risk of hepatocellular carcinoma (HCC), regardless of fatty liver or cirrhosis at baseline and on-treatment virological response (VR), according to a recent study.
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Among patients with nonvalvular atrial fibrillation (AF), treatment with apixaban was associated with a lower rate of ischaemic stroke, systemic embolism, and major bleeding compared with rivaroxaban, according to a large study assessing patients in routine care.