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[HKU Medical Grand Rounds] The other side of PPIs, beta-blockers and statins

Dr. Michael Kwan-Lung Ko, Dr. Siu-Yin Wong, 20170710000000

Case 1: A 79-year-old male patient presented initially with acute coronary syndrome and newly diagnosed myeloproliferative neoplasm with high white blood cell and platelet counts. He was stabilized and subsequently discharged with dual antiplatelet therapy (DAPT) (aspirin plus clopidogrel) and hydroxyurea.

Case 2: A 62-year-old female patient with a history of decompensated cryptogenic cirrhosis presented with acute variceal haemorrhage with haematemesis. Emergency OGD revealed three columns of grade 3 oesophageal varices with fibrin clot noted on one of them.

Case 3: A 51-year-old female patient with a history of systemic lupus erythematosus and hyperlipidaemia was referred to our hepatology clinic for evaluation of deranged liver function.

[HKU Medical Grand Rounds] Fat in liver: Does it matter?

Dr. Loey Lung-Yi Mak, Dr. Michael Ka-Shing Cheung, Prof. Man-Fung Yuen, 20170119000000

A 61-year-old man was referred to our centre due to deranged liver function tests (LFT) in 2010. He had enjoyed good past health and had been asymptomatic all along. He worked as a banker and drank small amounts of alcohol on occasions. Upon admission, he was found to be obese with body mass index (BMI) of 36.2 kg/m². His blood pressure was 173/86 mm Hg. Physical examination was otherwise unremarkable.

[CUHK Medical Grand Rounds] Faecal microbiota transplantation in a patient with Clostridium difficile infection, ulcerative colitis and Clostridium difficile ileitis

Dr. Louis HS Lau, Dr. Kelvin LY Lam, Prof. Siew-Chien Ng, 20161215000000

This is the case of a 43-year-old Chinese gentleman with ulcerative pancolitis who was treated with oral mesalazine and azathioprine.

Tumour or not tumour – that is the question

Dr. Yuk-Tong Lee, Dr. Wai-Mo Hui, 20160812000000

A 73-year-old man presented with 1 week’s history of progressive epigastric pain. The pain was dull in nature and the patient reported no vomiting or radiation of pain. On presentation, the patient was found to have a low-grade fever (temperature, 37.8°C). There was no tea-coloured urine. The patient had enjoyed good past health except for a previous surgery for spinal injury.

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Mycobiome load highest in patients on steroids, antifungal therapy

4 days ago

Fungal microbiome, also called the mycobiome, appears to be highly variable in patients with well-characterized fungal diseases, a recent study has shown. Moreover, severe asthmatics have the highest fungal loads, along with those receiving steroid and antifungal therapy.

Fostemsavir improves virologic efficacy, immunologic response in HIV-1

Audrey Abella, 07 Aug 2018

The use of the investigational first-in-class attachment inhibitor fostemsavir led to improved baseline viral and CD4+ T-cell counts in patients with HIV-1 infection who had limited treatment options and were failing their current antiretroviral regimen, according to the subgroup analysis results of the BRIGHTE* study presented at AIDS 2018.