Gastroenterology

Top Medical News
Statins help preserve liver function in chronic liver disease
Pearl Toh, 21 hours ago
Statins can help preserve liver function in patients with chronic liver disease, according to two studies presented at AASLD 2021— showing that not only are statins protective for the heart, but also for the liver.
Dietary gluten restriction unlikely to prevent digestive system cancers
Yesterday
Gluten intake does not necessarily contribute to the digestive system cancer burden among adults without coeliac disease, according to a study.
Psoriasis ups risk of colorectal cancer
Yesterday
Patients with psoriasis appear to be at greater risk for developing colorectal cancer, suggests a recent study, noting how gastroenterology consultation and colonoscopic examination are indicated for such individuals presenting with bowel symptoms.
6-month single antiplatelet regimen after DAPT post-PCI may reduce GI injury
Roshini Claire Anthony, 2 days ago

Among patients who received 6 months of dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI), switching to a single antiplatelet therapy (SAPT) regimen for another 6 months resulted in less gastrointestinal (GI) injury than continuing DAPT, results of the OPT-PEACE trial showed.

Dupilumab benefits in EoE sustained through 52 weeks
Pearl Toh, 4 days ago
The anti–interleukin (IL)-4/-13 antibody dupilumab led to sustained improvements across symptomatic, histologic, and endoscopic measures of eosinophilic oesophagitis (EoE) out to 52 weeks, according to additional data from the LIBERTY EoE TREET trial presented at ACG 2021.
High-dose corticosteroid good for maintenance treatment in eosinophilic esophagitis
Jairia Dela Cruz, 4 days ago
Eosinophilic esophagitis patients are likely to experience histological relapse despite ongoing treatment with swallowed topical corticosteroid (STC), but relapse occurs later with high- than with low-dose STC without any increase in side effects, a study has found.
Obesity ups risk of early-onset colorectal cancer
Stephen Padilla, 5 days ago
Obese people are more likely to develop early-onset colorectal cancer (CRC), suggests a study, noting that the increasing prevalence of obesity in younger generations may significantly contribute to the increase in this disease.
Special Reports
Product Highlight - Salofalk
12 Mar 2021
SALOFALK – Mesalazine 1.5 g PR granules
From the throat to the gut: Essential learnings for physicians
10 Mar 2020
RB Health is committed to support healthcare quality improvement through CME activities that help physicians stay updated with the latest developments in medicine. At the RB symposium held in Kuala Lumpur, two distinguished speakers gave their insights into the management of acid reflux and sore throat – two of the most common reasons for patients to visit their doctors.
Relationship between tumour response to systemic therapy and overall survival in unresectable hepatocellular carcinoma
Dr Raghav Sundar, 09 Sep 2019

Overall survival (OS) is currently the primary criteria in assessing the efficacy of a cancer treatment. Dr Raghav Sundar, a consultant medical oncologist at the National University Hospital, Singapore, details the crucial role played by tumour response in evaluating treatment efficacy, with a focus on the multiple kinase inhibitor lenvatinib in the treatment of hepatocellular carcinoma (HCC).  

Role of genomics in colorectal cancers
Dr Joslyn Ngu, 04 Dec 2017

Advancements in genomics has paved the way for better classifications of colorectal cancers (CRC) and the use of precision therapy.

Product Highlight – Dukoral
12 Jul 2017
DUKORAL – Inactivated Vibrio cholerae O1 serogroup & recombinant cholera toxin B subunit (WC/rCTB) vaccine (oral) – AJ Biologics
Optimizing the management of
Helicobacter pylori infection
04 Jan 2017
Recently, randomized controlled trials and guidelines have brought to light the benefits of extending the duration of H. pylori treatment. Below are summaries of guidelines and trials examining the regimens used to manage the infection.
The role of direct-acting antivirals in the new era of hepatitis C treatment
14 Dec 2016
At the recent Annual Scientific Congress of the Malaysian Society of Gastroenterology and Hepatology (GUT 2016), held at Shangri-La Hotel, Kuala Lumpur, an expert from Hong Kong spoke on the role of direct-acting antivirals as well as pan-genotypic agents that are set to revolutionize hepatitis C treatment.
Conference Reports
Statins help preserve liver function in chronic liver disease
Pearl Toh, 27 Nov 2021
Statins can help preserve liver function in patients with chronic liver disease, according to two studies presented at AASLD 2021— showing that not only are statins protective for the heart, but also for the liver.
Dupilumab benefits in EoE sustained through 52 weeks
Pearl Toh, 23 Nov 2021
The anti–interleukin (IL)-4/-13 antibody dupilumab led to sustained improvements across symptomatic, histologic, and endoscopic measures of eosinophilic oesophagitis (EoE) out to 52 weeks, according to additional data from the LIBERTY EoE TREET trial presented at ACG 2021.
Vonoprazan trumps PPI in ridding off H. pylori
Pearl Toh, 18 Nov 2021
Vonoprazan-containing triple- or dual-therapy regimens are superior to lansoprazole triple therapy in eradicating Helicobacter pylori (H. pylori), according to the phase III pHalcon-HP study presented at ACG 2021.
Long-term TAF works against resistant HBV, poses no excess cardiovascular risk
Jairia Dela Cruz, 17 Nov 2021
Tenofovir alafenamide (TAF) shows sustained safety and efficacy in heavily pretreated patients with multidrug-resistant hepatitis B virus (HBV) through 3 years of treatment, albeit leading to elevations in cholesterol levels.
Pandemic burnout hounds hepatology providers
Stephen Padilla, 17 Nov 2021
Burnout is experienced by nearly half (~40 percent) of hepatology providers during the COVID-19 pandemic, as shown by the negative impact of emotional well-being, including work fulfilment and satisfaction, according to a study.
Double trouble: Alcohol-related liver diseases take a turn for the worse during COVID-19
Elvira Manzano, 15 Nov 2021
Higher intake of alcohol and reduced care during the COVID-19 pandemic have triggered a spike in alcohol-related liver diseases, leading to some serious consequences, according to new research.
Upadacitinib scores big in UC
Elvira Manzano, 14 Nov 2021
The oral Janus kinase 1 (JAK1) inhibitor upadacitinib scores big in ulcerative colitis (UC), with promising results from U-ACCOMPLISH, one of two phase III trials completed for the drug.