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Top Medical News
While uncommon, lower gastrointestinal bleeding (LGIB) in patients with cirrhosis appears to worsen mortality risk, a new study has found.
Proton pump inhibitors (PPIs) may increase susceptibility to osteoporotic fractures in elderly women as compared with histamine-2 receptor antagonists (H2RAs), especially those who have used PPIs for at least a year, a recent study in Korea has found.
Use of the bile acid sequestrant IW-3718 as an adjunct to proton pump inhibitor (PPI) therapy is well tolerated and reduces heartburn and regurgitation symptoms in patients with refractory gastro-oesophageal reflux disease (GERD), according to the results of a trial.
Real-world data from the PCORnet* Bariatric Study suggest that Roux-en-Y gastric bypass (RYGB) may be preferable to sleeve gastrectomy (SG) in inducing and maintaining type 2 diabetes (T2DM) remission.
Exposure to nitroimidazole appears to mitigate the efficacy of nitroimidazole-based triple regimen, but not quadruple therapy, in patients with Helicobacter pylori infection, results of a study have shown.
Full-spectrum endoscopy (FUSE) is more effective than oesophagogastroduodenoscopy (OGD) in terms of precise visualization of blind spots in the duodenum, a study has shown.
A phase III study has shown the noninferiority of the potassium-competitive acid blocker vonoprazan to the proton pump inhibitor (PPI) lansoprazole for the management of erosive oesophagitis (EO) in an Asian* cohort.
Special Reports
RB Health is committed to support healthcare quality improvement through CME activities that help physicians stay updated with the latest developments in medicine. At the RB symposium held in Kuala Lumpur, two distinguished speakers gave their insights into the management of acid reflux and sore throat – two of the most common reasons for patients to visit their doctors.
At the recent Takeda Malaysia Vocinti® (vonoprazan) launch, held in conjunction with the Annual Scientific Meeting of the Malaysian Society of Gastroenterology and Hepatology - GUT 2019 at Shangri-La Kuala Lumpur, Professor Akihito spoke about vonoprazan’s merits as an alternative to conventional proton pump inhibitors.
Overall survival (OS) is currently the primary criteria in assessing the efficacy of a cancer treatment. Dr Raghav Sundar, a consultant medical oncologist at the National University Hospital, Singapore, details the crucial role played by tumour response in evaluating treatment efficacy, with a focus on the multiple kinase inhibitor lenvatinib in the treatment of hepatocellular carcinoma (HCC).
All Helicobacters are urease-positive, able to convert aminoacids and urea into ammonia to neutralize stomach acid, andhighly mobile – characteristics that help them invade the mucosallayer to evade the body’s immune response. Helicobacter pylori(H. pylori) is linked to peptic ulcer disease, chronic gastritis,gastric mucosa-associated lymphoid tissue lymphoma, andearly gastric cancer. The infection rate of H. pylori is over 80% indeveloping countries and 20–50% in industrialized nations, withover 4.4 billion people testing positive for the bacteria in 2015.1,2
There is an increasing number of studies that shed light on the importance of our gut microbiota. Probiotics are live microorganisms that confer health benefits on the host when administered in adequate amounts. With new data emerging about their proposed benefits in maintaining intestinal health, probiotics continue to gain popularity amongst consumers.
Advancements in genomics has paved the way for better classifications of colorectal cancers (CRC) and the use of precision therapy.
DUKORAL – Inactivated Vibrio cholerae O1 serogroup & recombinant cholera toxin B subunit (WC/rCTB) vaccine (oral) – AJ Biologics
Conference Reports
Some patients with colitis are more likely than others to develop cuffitis after proctocolectomy with ileal pouch-anal anastomosis (IPAA), according to a retrospective study presented at the annual Crohn’s & Colitis Congress.
Treatment with ustekinumab has been shown to be effective for ulcerative colitis (UC) in a real-world setting, according to a recent study presented at the 2020 Crohn’s and Colitis Congress (CCC 2020).
E-cigarette use remains low among adult patients with inflammatory bowel disease (IBD), and among these users, conventional cigarette smoking still remains prevalent, according to a recent study presented at the Crohn’s and Colitis Congress (CCC) 2020.
Use of proton pump inhibitors (PPIs) among patients with Crohn’s disease (CD) could increase their risk of interval flare and is associated with nonremission status, according to a study presented at the 2020 Crohn’s and Colitis Congress (CCC 2020).
Patients with Crohn’s disease (CD) seem to die at a younger age than people without inflammatory bowel disease (IBD), while those with ulcerative colitis (UC) die later, according to a recent study presented at the Crohn’s and Colitis Congress (CCC) 2020.
Among patients with ulcerative colitis (UC), vedolizumab serum concentrations in the fifth week after treatment initiation appear to have been higher in those who do vs do not show response in the sixth week, according to interim data from ENTERPRET study presented at the 2020 Crohn’s and Colitis Congress (CCC).
A diet low in fat and high in fibre seems well tolerated in patients with ulcerative colitis, not contributing to increased inflammation while significantly increasing populations of Faecalibacterium prausnitzii, according to a study presented at the 2020 Crohn's & Colitis Congress.
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