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Gastroenterology
Top Medical News
Once-weekly injection of the GLP-1* agonist semaglutide, on top of endoscopic sleeve gastroplasty (ESG), led to a greater weight loss and better glucose control vs ESG alone in patients with diabetes and excess weight but are not candidates for bariatric surgery, a new study has shown.
Adding the antifoaming agent simethicone to the bowel preparation regimen leads to improvement in bowel cleanliness quality and detection rate of polyps (PDR) but not adenomas (ADR), reports a recent study. There are no statistically significant differences seen in withdrawal time, cecal intubation time, and cecal intubation rate.
Coeliac disease cases among school age children have doubled over two and a half decades, and without a wider screening strategy, most cases will remain undiagnosed, as shown in the CELI SCREEN trial.
A recent European survey has found major discrepancies and gaps in hospital policies and procedures to prevent the direct transmission of hepatitis B virus (HBV) from mother to child, particularly before and after birth.
Subcutaneous administration of the infliximab biosimilar CT-P13 yields similar safety, efficacy, and immunogenicity profiles compared with the intravenous route, a recent study has found.
Early identification of dysphagia following acute stroke appears to have significant protective health benefits, such as minimizing the risks of pneumonia, mortality, overall dependency, and hospitalization duration, according to the results of a systematic review and meta-analysis.
Levels of the ATP7B peptide identifies Wilson disease with high reliability and can help reduce ambiguity regarding the diagnosis of the disease, a recent study has found.
Special Reports
SALOFALK – Mesalazine 1.5 g PR granules
RB Health is committed to support healthcare quality improvement through CME activities that help physicians stay updated with the latest developments in medicine. At the RB symposium held in Kuala Lumpur, two distinguished speakers gave their insights into the management of acid reflux and sore throat – two of the most common reasons for patients to visit their doctors.
At the recent Takeda Malaysia Vocinti® (vonoprazan) launch, held in conjunction with the Annual Scientific Meeting of the Malaysian Society of Gastroenterology and Hepatology - GUT 2019 at Shangri-La Kuala Lumpur, Professor Akihito spoke about vonoprazan’s merits as an alternative to conventional proton pump inhibitors.
Overall survival (OS) is currently the primary criteria in assessing the efficacy of a cancer treatment. Dr Raghav Sundar, a consultant medical oncologist at the National University Hospital, Singapore, details the crucial role played by tumour response in evaluating treatment efficacy, with a focus on the multiple kinase inhibitor lenvatinib in the treatment of hepatocellular carcinoma (HCC).
All Helicobacters are urease-positive, able to convert aminoacids and urea into ammonia to neutralize stomach acid, andhighly mobile – characteristics that help them invade the mucosallayer to evade the body’s immune response. Helicobacter pylori(H. pylori) is linked to peptic ulcer disease, chronic gastritis,gastric mucosa-associated lymphoid tissue lymphoma, andearly gastric cancer. The infection rate of H. pylori is over 80% indeveloping countries and 20–50% in industrialized nations, withover 4.4 billion people testing positive for the bacteria in 2015.1,2
Advancements in genomics has paved the way for better classifications of colorectal cancers (CRC) and the use of precision therapy.
DUKORAL – Inactivated Vibrio cholerae O1 serogroup & recombinant cholera toxin B subunit (WC/rCTB) vaccine (oral) – AJ Biologics
Conference Reports
Once-weekly injection of the GLP-1* agonist semaglutide, on top of endoscopic sleeve gastroplasty (ESG), led to a greater weight loss and better glucose control vs ESG alone in patients with diabetes and excess weight but are not candidates for bariatric surgery, a new study has shown.
Coeliac disease cases among school age children have doubled over two and a half decades, and without a wider screening strategy, most cases will remain undiagnosed, as shown in the CELI SCREEN trial.
A recent European survey has found major discrepancies and gaps in hospital policies and procedures to prevent the direct transmission of hepatitis B virus (HBV) from mother to child, particularly before and after birth.
In obese patients without gallstones, a 6-month treatment course of ursodeoxycholic acid (UDCA) following bariatric surgery may reduce their likelihood of developing symptomatic gallstones, according to findings of the UPGRADE trial from The Netherlands presented at DDW 2021.
Children whose mothers had taken fish oil supplements during the second half of pregnancy appeared to have better problem-solving skills and attention focus at age 10 vs those whose mothers had consumed folic acid alone or no supplements at all in a study presented at WCPGHAN 2021.
Adding bemarituzumab to mFOLFOX6 significantly improved survival outcomes and response rate compared with mFOLFOX6 alone in patients FGFR2b-positive, HER2-negative gastric cancer, according to the FIGHT study presented at the 2021 ASCO GI Cancer Symposium.
Results of a single-centre study in the UK have suggested that patients receiving systemic anticancer therapy for gastrointestinal (GI) cancers could continue their treatment during the COVID-19 pandemic.