Acute gastroenteritis is a diarrheal disease of rapid onset.
Viruses are one of the common causes of acute gastroenteritis.
Rotavirus, norovirus/"Norwalk-like" virus, sapovirus, enteric adenovirus serotypes 40 and 41, astrovirus, calicivirus and enterovirus are the established viral agents causing gastroenteritis.
Rotavirus is the most common pathogen causing diarrhea in patients 3-24 months old.
Patients <3 months old are protected by maternal rotavirus antibodies that are passed transplacentally and possibly by breastfeeding.
Transmission is through fecal-oral route.
Rotavirus (RV) is highly contagious. Globally, 2 million children are hospitalized and more than 500,000 die annually from RV associated gastroenteritis. Therefore, vaccination is imperative for the prevention of RV infections.
Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.