Food allergy is an adverse reaction due to a specific immune response
occurring reproducibly upon exposure to certain foods. It occurs minutes
to hours after food consumption.
Immunological mechanisms can be IgE mediated, non-IgE mediated or mixed IgE and non-IgE mediated.
It may be life-threatening and is the most common cause of anaphylaxis in children.
It should be differentiated from food intolerance in which adverse
reactions from exposure to food arise from non-immunological mechanisms.
Children and adolescents with severe peanut allergy treated with the peanut-derived oral biologic immunotherapy drug AR101 may improve their tolerance to peanut protein with reduced symptom severity, according to the phase III PALISADE* trial.
Exclusive breastfeeding for 6 months is advisable for allergy prevention, while hydrolyzed formulas (HFs) with reduced allergenicity may be considered for mothers who are unable or choose not to breastfeed, an expert recommended.
Combining an initial 16-week course of the monoclonal antibody omalizumab with oral immunotherapy (OIT) significantly and safely improves desensitization to the offending foods compared with OIT alone in children and adolescents with multiple food allergies, a new study found.
The presence of eczema or atopic dermatitis with concurrent allergic sensitization at 1 year of age was associated with an increased risk of developing asthma and food allergy in later childhood at 3 years old, according to the CHILD* study.
High free sugar intake during pregnancy was associated with a heightened risk of allergy and allergic asthma in the children, independent of their sugar intake during early childhood, according to the ALSPAC* study.
Delivery of peanut protein through the skin by means of a wearable skin patch, an approach known as epicutaneous immunotherapy, is safe and shows promise for treating peanut allergy, especially in young children, according to interim results of an ongoing study.
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Baseline body mass index (BMI) and, to a lesser extent, school socioeconomic status are associated with subsequent weight status in schoolchildren, according to a study. Lifestyle behaviours show a lower effect as compared with prior BMI, but children with a healthier lifestyle have a reduced risk of overweight and obesity at follow-up.
Use of electronic vapour products (EVP), or vaping, has been associated with an increased likelihood of engaging in sexual and substance-use risk behaviours among US teenagers, according to data from the 2017 National Youth Risk Behaviour Survey presented at the Paediatric Academic Societies (PAS) 2019 Meeting.
Parenteral antibiotic therapy duration for bacteraemic urinary tract infection (UTI) in young infants may be safely shortened, according to a recent study showing that recurrence and readmission or emergency department revisitation rates are comparable between a ≤7-day and a longer therapy course.