Food allergy is an adverse reaction due to a specific immune response
occurring reproducibly upon exposure to certain foods. It occurs minutes
to hours after food consumption.
Immunological mechanisms can be IgE mediated, non-IgE mediated or mixed IgE and non-IgE mediated.
It may be life-threatening and is the most common cause of anaphylaxis in children.
It should be differentiated from food intolerance in which adverse
reactions from exposure to food arise from non-immunological mechanisms.
Children and adolescents with severe peanut allergy treated with the peanut-derived oral biologic immunotherapy drug AR101 may improve their tolerance to peanut protein with reduced symptom severity, according to the phase III PALISADE* trial.
Exclusive breastfeeding for 6 months is advisable for allergy prevention, while hydrolyzed formulas (HFs) with reduced allergenicity may be considered for mothers who are unable or choose not to breastfeed, an expert recommended.
Combining an initial 16-week course of the monoclonal antibody omalizumab with oral immunotherapy (OIT) significantly and safely improves desensitization to the offending foods compared with OIT alone in children and adolescents with multiple food allergies, a new study found.
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Antiviral treatment with tenofovir alafenamide fumarate (TAF) during pregnancy in highly viraemic mothers effectively prevents mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with no safety concerns, according to two studies presented during the AASLD 2020 Liver Meeting.
A multifaceted intervention that consists of a simplified dosing handout, a teaching session, teach-back, and provision of a standardized dosing device facilitates safe dosing of liquid acetaminophen and ibuprofen by parents or guardians of children discharged from the emergency department, according to a study.
A 4-week course of amoxicillin-clavulanate in children with protracted bacterial bronchitis (PBB) does not improve cough resolution rates compared with a 2-week course, according to a study from Australia. However, the longer course may significantly extend time to first cough exacerbation.