Infectious Diseases Search
Infectious Diseases Infectious Diseases
febrile%20neutropenia
FEBRILE NEUTROPENIA
Febrile neutropenia is having a fever of ≥38.3 ºC or ≥38 ºC over an hour and neutropenia that is having an absolute neutrophil count (ANC) of <500 neutrophils/mm3 or an ANC <1000 neutrophils/mm3 expected to decline to ≤500 neutrophils/mm3 over the next 48 hours.
The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia.
Fever is frequently the only indication of infection in the neutropenic patient.

Febrile%20neutropenia Signs and Symptoms

Definition

Fever
  • Defined as single oral temperature ≥38.3 °C (101°F) or 2 consecutive readings ≥38.2 °C (100.4°F) over 1-2 hours
Neutropenia
  • Defined as an absolute neutrophil count (ANC) of ≤500/μL (<0.5 x 109/L) or an ANC ≤1000/μL expected to decline to ≤500/μL (<0.5 x 109/L) over the next 48 hours
  • Severe neutropenia is defined as ANC <500/μL (<0.5 x 109/L)
  • Profound neutropenia is defined as ANC <100/μL (<0.1 x 109/L)

The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Infectious Diseases - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
COVID-19 pandemic causes drop in cardiovascular diagnostic testing
2 days ago
Diagnosis of heart diseases has abruptly and significantly decreased across the globe due to the coronavirus disease 2019 (COVID-19) pandemic, especially affecting poorer countries, reveals a study.
Pfizer and BioNTech are testing 4 novel vaccines in Europe and US.
Pank Jit Sin, 13 May 2020
A trial vaccine for the prevention of COVID-19 is underway with the first US participants being dosed in the Phase 1/2 clinical trial. Known as the BNT162 vaccine programme, the trials are a collaboration between Pfizer Inc. and BioNTech SE, and is part of a global development programme with Germany and the US taking the lead in having the first cohorts to be vaccinated. Germany started the study 1 week earlier.