Febrile Neutropenia Signs And Symptoms

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FEBRILE NEUTROPENIA

Febrile neutropenia is having a fever of ≥38.3 ºC or ≥38 ºC over an hour and neutropenia that is having an absolute neutrophil count (ANC) of <500 neutrophils/mm³ or an ANC <1000 neutrophils/mm³ expected to decline to ≤500 neutrophils/mm³ over the next 48 hours.
The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia.
Fever is frequently the only indication of infection in the neutropenic patient.

Signs and Symptoms

Definition

Fever

Defined as single oral temperature ≥38.3 °C or 2 consecutive readings ≥38.2 °C over 1-2 hours

Neutropenia

Defined as an absolute neutrophil count (ANC) of <500 neutrophils/mm³ or an ANC <1000 neutrophils/mm³ expected to decline to ≤500 neutrophils/mm³ over the next 48 hours

The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia

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