Febrile%20neutropenia Signs and Symptoms

• Defined as single oral temperature ≥38.3 °C (101°F) or 2 consecutive readings ≥38.2 °C (100.4°F) over 1-2 hours

• Defined as an absolute neutrophil count (ANC) of ≤500/μL (<0.5 x 10⁹/L) or an ANC ≤1000/μL expected to decline to ≤500/μL (<0.5 x 10⁹/L) over the next 48 hours
• Severe neutropenia is defined as ANC <500/μL (<0.5 x 10⁹/L)
• Profound neutropenia is defined as ANC <100/μL (<0.1 x 10⁹/L)

The risk of febrile neutropenia is directly proportional to the duration and severity of neutropenia