Epilepsy is a clinical multiaxial diagnosis.
Epileptic seizure is a transient occurrence of signs/symptoms brought about by abnormal excessive or synchronous neuronal activity in the brain.
It is recommended that all patients having a first seizure be referred as soon as possible to a specialist to ensure accurate and early diagnosis and initiation of treatment appropriate to the needs of the patients.
Measuring heart rate variability (HRV) using a wearable echocardiography (ECG) device shows promise in detecting seizures, including the nonconvulsive episodes, proving to have high sensitivity and low false alarm rate during the night, according to data from a phase II validation study.
Between the two most common invasive monitoring approaches, stereoelectroencephalography (SEEG) leads to fewer surgical resections yet more favourable seizure freedom outcomes in epilepsy patients scheduled to undergo resections compared with subdural electrodes, as reported in a systematic review. Additionally, SEEG is associated with lower morbidity and mortality.
Raving at electronic dance music festivals that commonly use stroboscopic light effects may be risky for individuals who are susceptible to epileptic seizures, with a recent study suggesting that strobe lights carry a threefold increased seizure hazard.
Child-onset epilepsy may negatively affect social outcomes, and individuals who still experience seizure as adults are least likely to start a family and have trouble conceiving, a study from Finland has found.
Midazolam nasal spraydelivers prompt and prolonged seizure control with a favourable safety profile in the outpatient treatment of patients experiencing a seizure cluster, according to the results of the phase III ARTEMIS-1* trial.
New drug applications approved by US FDA as of 16 - 31 May 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
A low sodium concentration in the blood is commonly observed in patients with epilepsy, with moderate and severe hyponatraemia associated with reduced bone mineral density in the lumbar spine, a study has found.
Associate Professor Reshma A Merchant, Head & Senior Consultant of the Division of Geriatric Medicine at the National University Hospital, Singapore, speaks with Audrey Abella to discuss the challenges associated with dementia, its impact on the ageing population, and how this condition can be best managed in primary care.