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EPILEPSY (PEDIATRIC)

Epileptic seizure is a transient occurrence of signs or symptoms that is due to abnormal excessive or synchronous neuronal activity in the brain.
Epilepsy is a disorder that is characterized by a persistent predisposition of the brain to generate epileptic seizures.
This condition may cause neurobiologic, cognitive, psychological and social disturbances.
It is recommended that all patients having a first seizure be referred to a specialist as soon as possible.

Epilepsy (Pediatric) Drug Information

Drug Information

Pharmaniaga Phenytoin Na

Phenytoin

Indication: Control of tonic-clonic (grand mal) status epilepticus. Prevention & treatment of seizures during or follo...

MIMS Class: Anticonvulsants

Pharmaniaga LifeScience [ Pharmaniaga Logistics ]

Neurontin

Gabapentin

Indication: Adjunctive therapy in treatment of partial seizures w/ & w/o secondary generalization in adults & chil...

MIMS Class: Anticonvulsants / Drugs for Neuropathic Pain

Pfizer [ Zuellig Pharma ]

Topamax

Topiramate

Indication: Monotherapy in patients w/ newly diagnosed epilepsy or for conversion to monotherapy in patients w/ epilepsy. ...

MIMS Class: Anticonvulsants / Antimigraine Preparations

Janssen [ Zuellig Pharma ]

Zonegran

Zonisamide

Indication: Monotherapy for partial seizures w/ or w/o secondary generalisation in adults w/ newly diagnosed epilepsy. Adj...

MIMS Class: Anticonvulsants

Eisai [ DKSH ]

Diazepam Idaman

Diazepam

Indication: Anxiety, acute alcohol w/drawal symptoms, pre-op procedures to relieve anxiety & tension; adjunct prior to...

MIMS Class: Anxiolytics

Idaman Pharma [ Pharmaniaga Logistics ]

Dilantin Capsule

Phenytoin

Indication: Control of generalised tonic-clonic (grand mal) epilepsy & psychomotor seizures.

MIMS Class: Anticonvulsants

Pfizer [ Zuellig Pharma ]

Dilantin Steri-Vial

Phenytoin

Indication: Control of tonic-clonic (grand mal) status epilepticus. Prevention & treatment of seizures occurring durin...

MIMS Class: Anticonvulsants

Pfizer [ Zuellig Pharma ]

Fycompa

Perampanel

Indication: Adjunctive treatment of partial-onset seizures w/ or w/o secondarily generalized seizures in patients ≥12 y...

MIMS Class: Anticonvulsants

Eisai [ DKSH ]

Inovelon

Rufinamide

Indication: Adjunctive treatment of seizures associated w/ Lennox-Gaustaut syndrome in adults & childn ≥4 yr.

MIMS Class: Anticonvulsants

Eisai [ DKSH ]

Keppra

Levetiracetam

Indication: Monotherapy in treatment of partial onset seizures w/ or w/o secondary generalisation in patients from 16 yr w...

MIMS Class: Anticonvulsants

GlaxoSmithKline [ Zuellig Pharma ]

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High dose comparable to lower doses of ACE inhibitors for heart failure

Jairia Dela Cruz, 16 Sep 2020

In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.