An inverse relationship exists between breastfeeding and risk of incident endometriosis among women who experienced at least one pregnancy that lasted at least 6 months, according to a recent study. Postpartum amenorrhoea partially, but not fully, influences such association, suggesting that breastfeeding may affect the risk of endometriosis both through amenorrhoea and other mechanisms.
Associate Professor Tan Hak Koon, Head and Senior Consultant, and Dr Andy Tan, Associate Consultant from the Department of Obstetrics & Gynaecology at Singapore General Hospital (SGH) speak about the causes of endometriosis and the importance of early diagnosis and treatment.
In Singapore, advanced breast cancer (aBC) is the leading cause of cancer death in women 30–49 years of age. For premenopausal women diagnosed with hormone receptor (HR)-positive, HER2-negative BC, cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors provide new hope. Currently, ribociclib is the only CDK4/6 inhibitor studied in the first-line setting for premenopausal women with HR+/HER2- aBC, in the phase III MONALEESA-7 trial. Two experts, Dr Wong Seng Weng, Medical Director & Consultant Medical Oncologist at The Cancer Centre, Paragon Medical & Mount Elizabeth Novena Specialist Centre, and Dr Lee Guek Eng, Senior Consultant & Specialist in Medical Oncology at Icon Cancer Centre and Program Director of the Young Women Cancer Program, weigh in with their views on managing premenopausal women with aBC.