Prolonged ingestion of a high-dose dietary fructose does not result in relevant metabolic consequences in the presence of a stable energy intake, slightly lower body weight and potentially incomplete absorption of orally administered fructose load, according to a study.
The substitution of proline-12 to alanine (Pro12Ala) in the proliferator-activated receptorγ2 gene (PPARγ2) appears to be protective against albuminuria and diabetic nephropathy in type 2 diabetes mellitus (T2DM) patients, a new study has found.
Reducing low-density lipoprotein cholesterol (LDL-C) levels may cut the risk of atherosclerotic cardiovascular disease events in type 2 diabetes patients with metabolic dyslipidaemia, a recent study has shown.
Adults with type 1 diabetes mellitus (T1DM) may fare better with continuous subcutaneous insulin infusion (CSII) therapy, which is associated with lower glycated haemoglobin (HbA1c) variability compared with multiple daily injection (MDI) treatment, as shown in a recent study.
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
Use of the feminizing hormone therapy medroxyprogesterone acetate (MPA) results in minimal side effects, unchanged oestradiol levels and a decline in testosterone in a cohort of transwomen, a study has found.