A recent study has shown no significant rise in trimethylamine-N-oxide (TMAO) or platelet reactivity in healthy individuals who consumed four eggs daily, despite high choline content in egg yolks. However, choline bitartrate supplements providing similar total choline has increased both TMAO and platelet reactivity, indicating that the form and source of dietary choline differentially contribute to systemic TMAO levels and platelet responsiveness.
Empagliflozin significantly reduces the risk of cardiovascular (CV) death or hospitalization for heart failure (HHF) vs placebo in patients with heart failure with preserved ejection fraction (HFpEF) with or without diabetes, according to results of the EMPEROR-Preserved trial presented at the European Society of Cardiology (ESC) Congress 2021.
Regular intake of saturated fatty acids (SFA) from meat could increase cardiovascular disease (CVD) risk whereas dairy sources, grains, fruits, and vegetables could be cardio-protective, suggests a study in the UK.
Dual sodium-glucose co-transporter 1/2 (SGLT1/2) inhibition with licogliflozin appears to produce reductions in hyperinsulinaemia and hyperandrogenaemia in women with polycystic ovary syndrome, as shown in a phase II study.
Though rare, severe nonproliferative and proliferative diabetic retinopathy remain public health threats, and holistic strategies are needed to control diabetes and other lifestyle risk factors, such as smoking and blood pressure, a new Iran study has found.