For patients with type 1 diabetes (T1D), switching to faster insulin aspart may improve glycated haemoglobin (HbA1c), time-in-range (TIR), and time in hyperglycaemia, without posing serious hypoglycaemia risks, according to a new study.
In patients with chronic heart failure with reduced ejection fraction (HFrEF), empagliflozin reduced the risk of cardiovascular (CV) death or heart failure hospitalization (HHF) and decline in estimated glomerular filtration rate (eGFR), results of the EMPEROR-Reduced* trial showed.
Adding dapagliflozin to standard of care (SOC) significantly reduces the risk of worsening kidney function, death due to kidney or cardiovascular (CV) disease, and all-cause mortality compared with SOC alone in patients with chronic kidney disease (CKD), regardless of whether they have type 2 diabetes (T2D), reveals the DAPA-CKD* trial — showing dapagliflozin charting new territories from diabetes to the renal realm.
The combination of pitavastatin and fenofibrate appears to have superior effect on non-high-density lipoprotein cholesterol (non–HDL-C), as well as other lipids, compared with a statin alone in high-risk patients with mixed dyslipidemia, according to a study.
Several factors, including body mass index (BMI), diabetes mellitus, and age, are associated with the risk of progression from prehypertension to hypertension among middle-aged and elderly adults, according to a 12-year Korean cohort study.
More than two-thirds of Asian patients with ischaemic diabetic heel ulcers survived without requiring an amputation at 1 year following lower limb revascularization surgery — a rate better than previously reported in the literature, according to a local study.
Patients with multivessel coronary artery disease (CAD) and diabetes treated with coronary artery bypass grafting (CABG) have improved long-term mortality and freedom from major cardiovascular and cerebrovascular events (MACCEs) compared to those treated with percutaneous coronary intervention (PCI), according to a study.
Metformin use in patients with type 2 diabetes (T2D) appears to contribute to an early reduction in haemoglobin levels, which in turn leads to a higher incidence of moderate anaemia, according to data from the MASTERMIND study.
Individuals with obesity are likely to maintain a healthy metabolic status on a vegetarian or vegan diet, according to a study. But simply adhering to this dietary pattern does not assure better outcome, because some plant-based foods are less nutritious.
This second issue revisits the impact EMPA-REG OUTCOME had on clinical
practice and helps readers discover how it gives life back to patients
through its cardiovascular indication. Learn how it was approved and the
mechanisms for its cardiovascular benefits.
Zinc supplementation significantly lowers key glycaemic indicators, particularly fasting glucose (FG) in individuals with diabetes and in those who received an inorganic supplement, results of a systematic review and meta-analysis have shown.
Higher levels of exercise appear to be associated with a lower risk of all-cause mortality in adults with type 2 diabetes (T2D) compared with no exercise at all, according to a study presented at EASD 2020.