Type 2 diabetes mellitus (T2DM) contributes to a heightened risk of death, hepatic decompensation, and hepatocellular carcinoma (HCC) among patients with nonalcoholic steatohepatitis (NASH) and cirrhosis, but the good news is that metformin may cut the risk of these adverse outcomes, a study has found.
Once-daily 14 mg oral semaglutide yields greater reduction in HbA1c and body weight than weekly 0.75 mg subcutaneous dulaglutide and is well tolerated in a Japanese population with uncontrolled type 2 diabetes (T2D), according to the PIONEER 10 study.
There is a high incidence of psychiatric comorbidities among gender nonconforming teenagers, with about two-thirds and one-third experiencing depression and anxiety, respectively, according to a study presented at ENDO 2020.
Combining the oral GnRH* receptor antagonist relugolix together with oestradiol and the progestin norethindrone helps protect against bone loss induced by oestrogen deprivation associated with the use of GnRH receptor antagonist monotherapy for treating heavy menstrual bleeding, according to the LIBERTY studies released during the ACOG 2020 Meeting.
Daily intake of sugar-sweetened beverages was associated with elevated triglyceride levels and lower HDL cholesterol levels, both of which are risk factors for cardiovascular disease (CVD), according to the Framingham Heart Study with up to 23 years of follow-up.
Fasting-mimicking diet (FMD) cycles in combination with endocrine therapy (ET) cause metabolic changes in hormone receptor (HR)-positive breast cancer patients analogous to those observed in animal models, where they are associated with anticancer activity.
While bariatric surgery is increasingly recommended in obese teens to achieve significant, sustained weight loss and resolve comorbid diseases, a study has shown a major downside to the procedure: nutritional deficiencies, specifically in iron and vitamin B12.
Consumption of two eggs a day for breakfast for 6 days per week leads to less reduction in low-density lipoprotein cholesterol (LDL-C) and more lowering of systolic blood pressure (SBP) in adults compared to nonegg-based, energy-matched, control foods higher in carbohydrates (CHO), according to a study.