Genetic predisposition to elevated blood pressure (BP) may affect BP changes in response to weight-loss diets, such that individuals with higher genetic susceptibility exhibit less decrease in BP levels, a study has found. Moreover, this effect differs by protein intake.
Replacing sucrose and fructose with starch results in reduced low-density lipoprotein cholesterol (LDL-C) concentrations, reveals a study. Moreover, substitution of fructose with glucose provides a beneficial effect on insulin resistance as well as uric acid concentrations.
Hypertensive patients have a higher risk of new-onset type 2 diabetes mellitus (T2DM) than their nonhypertensive counterparts, a study has shown. Such risk does not differ between patients with controlled hypertension, uncontrolled hypertension or apparent therapy-resistant hypertension (aTRH).
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.
Use of long-acting pasireotide in the treatment of Cushing’s disease (CD) appears to be effective and safe, yielding sustained biochemical and clinical improvements, with a safety profile that is favourable and consistent with that reported during the first year of therapy, according to data from the open-label extension phase of a phase III study.
In neonates at risk of congenital adrenal hyperplasia, prenatal dexamethasone exposure appears to reduce virilization but exerts no effect on physical outcomes, cognitive functions, behavioural problems and temperament, according to the results of a meta-analysis.
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.