Among patients with type 2 diabetes mellitus (T2DM), plasma levels of xanthine oxidoreductase (XOR) share a close relationship with circulating levels of liver transaminases, a new study has found. This interaction suggests that XOR may find use as an indicator of liver damage in these patients.
Body mass index (BMI) values that are above average and the development of overweight from childhood to adulthood are risk factors for gestational hypertension and pre-eclampsia, but normalizing BMI from childhood to conception reduces such risks, according to a study.
Accelerometer-assessed moderate-to-vigorous physical activity (MVPA) at baseline shows an inverse relationship with incident diabetes among individuals aged ≥50 years, a recent study involving a US Hispanic/Latino population has found.
Patients with acute ischaemic stroke undergoing endovascular treatment are at heightened risk of poor functional outcome and symptomatic intracranial haemorrhage (sICH) in the presence of hyperglycaemia at admission, a study has found.
Undergoing in-facility physical activity (PA) programmes initiated before the 20th week of gestation helps reduce the risk of developing gestational diabetes mellitus (GDM) among high-risk mothers, according to the results of a meta-analysis.
Treatment with sodium-glucose cotransporter-2 inhibitors (SGLT2i) results in a lower risk of clinically relevant cardiovascular death, heart failure (HF) hospitalization, and HF symptoms with similar rates of adverse events (AEs), results of a meta-analysis have shown.
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.
Invasive fungal infections, particularly those caused by Candida species, are common in hospitalized, immunocompromised, or critically ill patients and are associated with considerable morbidity and mortality.