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High-egg diet does not have adverse effects on cardiometabolic factors in T2D patients

Yesterday

There appears to be no adverse changes in cardiometabolic markers among individuals with prediabetes or type 2 diabetes (T2D) who consumed a 3-month high-egg weight-loss diet with a 6-month follow-up compared with those who consumed a low-egg weight-loss diet, suggests a recent study.

Elevated BMI predicts postoperative CSF leak following transsphenoidal procedures

Stephen Padilla, 4 days ago

Patients with elevated body mass index (BMI) are at risk of postoperative cerebrospinal fluid (CSF) leak following transsphenoidal procedures, reports a Singapore study. This is true even in an Asian population, where the definition of obesity varied from international standards. Therefore, BMI should be considered in the clinical decision-making process prior to such procedures.

Studies show lifestyle intervention plan for diabetes effective

Dr Joslyn Ngu, 4 days ago

The transcultural Diabetes Nutrition Algorithm (tDNA) which involves a structured low-calorie meal plan, diabetes-specific meal replacements and enhanced physical activity, is effective for weight loss in patients with type 2 diabetes, a local study shows. [BMJ Open Diabetes Res Care 2017;5(1):e000384. Doi:10.1136/bmjdrc-2016-000384th]

Pre-existing T2D, CKD increase mortality risk in heart failure

Roshini Claire Anthony, 5 days ago

Having both pre-existing type 2 diabetes (T2D) and chronic kidney disease (CKD) appears to raise the risk of all-cause and cardiovascular disease (CVD)-specific mortality in patients with heart failure, according to results of a Singapore study.

Perirenal fat useful for assessing cardiovascular risk in children

5 days ago

Perirenal fat is associated with carotid intima-media thickness, especially among overweight and obese children, and may thus represent a useful parameter for evaluating cardiovascular risk in the paediatric population, according to a study.

Plasma xanthine oxidase activity tied to insulin resistance, liver dysfunction in T2DM with MetS

15 Jun 2018

Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.

Cancer incidence rates higher in patients with acromegaly

Stephen Padilla, 15 Jun 2018

Patients with acromegaly, a rare disease caused by hypersecretion of growth hormone (GH) usually from a pituitary adenoma, have a slightly elevated risk of cancer, according to a cohort study. This finding is supported by a meta-analysis, but selection bias is present in some earlier studies.

Redefining diabetes management: Combining glycaemic control with cardiovascular protection to deliver better patient outcomes

31 May 2018

At the recent ‘Reinforced for the Glycaemic Challenge’ symposium held at Shangri-la Hotel, Kuala Lumpur, Associate Professor Dr Alexander Tan, Professor Dr Chee Kok Han and Dr Chan Siew Pheng shared their insights into the importance of achieving glycaemic control in patients with type 2 diabetes mellitus (T2DM), while simultaneously providing them with cardiovascular protection.

Optimizing hormone replacement therapy in menopause

05 Apr 2017

At a recent lunch symposium held in conjunction with the 1st Malaysian Advances in Women’s Health Congress 2016, Professor Dr Jamiyah Hassan imparted clinical updates and strategies for the optimization of hormone replacement therapy in menopausal women. Highlights from her presentation are summarized below.

The Future of Osteoporosis Management

20 Jan 2017

At the recent Malaysian Osteoporosis Society 2016 Clinical Practice Guideline (CPG) Meeting held on the 8th of October 2016 at Ibis Styles Ipoh, Dr Hew Fen Lee and Professor Dr Chan Siew Pheng presented clinical guidance on the management of osteoporosis, and discussed whether the benefits of treatment outweigh the risks.

Role of gliclazide MR today: Efficacy and safety you can trust

04 Jan 2017

At the Diabetes Asia 2016 Conference organized by the National Diabetes Institute, Professor Jean Claude Mbanya presented the case for why gliclazide modified release (MR; Diamicron® MR, Servier) should be the treatment of choice for early and aggressive control of type 2 diabetes (T2D).

Preventing 3 key heart failure risk factors in midlife may prolong disease-free survival

Pearl Toh, 07 Dec 2016

Preventing hypertension, diabetes, and obesity, which are the major risk factors for heart failure (HF), by ages 45 and 55 years may lower risks of incident HF and prolong HF-free survival, suggests data from the Cardiovascular Disease Lifetime Risk Pooling Project.

Gearing towards personalization of diabetes treatment

Dr. Joseph Delano Fule Robles, 11 Jun 2018

Diabetes mellitus (DM) is increasingly diagnosed in younger individuals. This poses challenges such as long exposure to diabetes and its complications and the need for tailor-made treatment protocols that fit a specific group of diabetic patients.

Low sperm count may signal health risk

Audrey Abella, 26 Apr 2018

Men with low total sperm count (TSC) have more issues to worry about other than fertility, according to an Italian study presented at ENDO 2018 in Chicago, Illinois, US, which identified an association between low TSC and poor metabolic, cardiovascular, and bone health.

Synthetic androgen shows promise as male birth control pill

Pearl Toh, 20 Apr 2018

The investigational oral synthetic androgen dimethandrolone undecanoate (DMAU) suppresses serum testosterone levels to near castrate levels and appears safe when taken once daily for a month, showing potential as a male contraceptive pill, according to a study.

Semaglutide confers significant weight loss in obese, nondiabetic patients

Roshini Claire Anthony, 18 Apr 2018

Individuals with obesity but without diabetes experienced significant weight reduction with daily doses of the glucagon-like peptide-1 receptor agonist semaglutide, according to a recent study presented at ENDO 2018.

Closed-loop insulin pump may improve glycaemic outcomes in children with T1D

Roshini Claire Anthony, 16 Apr 2018

The use of a hybrid closed-loop insulin pump, which has shown promise in improving glycaemic outcomes in adolescents and adults with type 1 diabetes, may also be beneficial in children, according to a study presented at ENDO 2018.

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