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Synthetic androgen shows promise as male birth control pill

Pearl Toh, 18 hours ago

The investigational oral synthetic androgen dimethandrolone undecanoate (DMAU) suppresses serum testosterone levels to near castrate levels and appears safe when taken once daily for a month, showing potential as a male contraceptive pill, according to a study.

Statin-induced reduction in LDL lowers stroke, transient ischaemic attack risk

15 hours ago

The composite risk of stroke and transient ischaemic attack appears to be reduced in the low-density lipoprotein (LDL) cholesterol level of 80–100 mg/dL, according to the posthoc analysis of the J-STARS (Japan Statin Treatment Against Recurrent Stroke) study.

Semaglutide confers significant weight loss in obese, nondiabetic patients

Roshini Claire Anthony, Yesterday

Individuals with obesity but without diabetes experienced significant weight reduction with daily doses of the glucagon-like peptide-1 receptor agonist semaglutide, according to a recent study presented at ENDO 2018.

CGM cost-effective in T1D patients on daily insulin injections

Elvira Manzano, 2 days ago

The use of continuous glucose monitoring (CGM) may be cost-effective in patients with type 1 diabetes (T1D) receiving daily multiple insulin injections, the *DIAMOND trial has shown.

Oestrogen-progestin OCPs, antiandrogens, insulin sensitizers improve hirsutism

2 days ago

Antiandrogens, insulin sensitizers and oestrogen-progestin oral contraceptive pills (OCPs) are all effective in the treatment of hirsutism, suggest the results of a systematic review and meta-analysis.

Closed-loop insulin pump may improve glycaemic outcomes in children with T1D

Roshini Claire Anthony, 3 days ago

The use of a hybrid closed-loop insulin pump, which has shown promise in improving glycaemic outcomes in adolescents and adults with type 1 diabetes, may also be beneficial in children, according to a study presented at ENDO 2018.

Optimizing hormone replacement therapy in menopause

05 Apr 2017

At a recent lunch symposium held in conjunction with the 1st Malaysian Advances in Women’s Health Congress 2016, Professor Dr Jamiyah Hassan imparted clinical updates and strategies for the optimization of hormone replacement therapy in menopausal women. Highlights from her presentation are summarized below.

The Future of Osteoporosis Management

20 Jan 2017

At the recent Malaysian Osteoporosis Society 2016 Clinical Practice Guideline (CPG) Meeting held on the 8th of October 2016 at Ibis Styles Ipoh, Dr Hew Fen Lee and Professor Dr Chan Siew Pheng presented clinical guidance on the management of osteoporosis, and discussed whether the benefits of treatment outweigh the risks.

Role of gliclazide MR today: Efficacy and safety you can trust

04 Jan 2017

At the Diabetes Asia 2016 Conference organized by the National Diabetes Institute, Professor Jean Claude Mbanya presented the case for why gliclazide modified release (MR; Diamicron® MR, Servier) should be the treatment of choice for early and aggressive control of type 2 diabetes (T2D).

Preventing 3 key heart failure risk factors in midlife may prolong disease-free survival

Pearl Toh, 07 Dec 2016

Preventing hypertension, diabetes, and obesity, which are the major risk factors for heart failure (HF), by ages 45 and 55 years may lower risks of incident HF and prolong HF-free survival, suggests data from the Cardiovascular Disease Lifetime Risk Pooling Project.

Part IV: Systolic Blood Pressure (BP) and the Combination of Indapamide Sustained Release (SR) and Amlodipine, an Endocrinologist’s Point of View

18 Nov 2016

The prevalence of hypertension is on the rise in Malaysia and many patients require more than one medication to control their BP. However, treatment adherence is a common issue in patient management, particularly when it comes to patients with multiple morbidities requiring numerous medications.¹ In this interview, MIMS Doctor spoke to a distinguished endocrinologist about systolic hypertension, diabetes and patient compliance.

Synthetic androgen shows promise as male birth control pill

Pearl Toh, 19 Apr 2018

Semaglutide confers significant weight loss in obese, nondiabetic patients

Roshini Claire Anthony, 18 Apr 2018

Closed-loop insulin pump may improve glycaemic outcomes in children with T1D

Roshini Claire Anthony, 16 Apr 2018

Higher risk of nonvertebral fracture following Roux-en-Y bypass vs gastric banding

Roshini Claire Anthony, 12 Apr 2018

Individuals with severe obesity who undergo Roux-en-Y gastric bypass (RYGB) may have a higher risk of nonvertebral fractures than those who undergo adjustable gastric banding (AGB), according to a study presented at the recent ENDO 2018 sessions.

Low-calorie liquid diet may help reverse diabetes

Elvira Manzano, 22 Jan 2018

A reversal of type 2 diabetes (T2D) may be possible with low-calorie liquid diet for up to 5 months, increased physical activity, and cognitive behavioural therapy, preliminary results of the DiRECT* trial has shown.

Diabetes drug combo tied to favourable outcomes

Audrey Abella, 18 Jan 2018

A titratable, fixed-ratio combination of insulin glargine 100 U/mL and the GLP-1* receptor agonist lixisenatide was associated with favourable glycaemic and gastrointestinal outcomes in patients with type 2 diabetes (T2D), according to several studies presented at IDF 2017.

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