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Top Medical News
Patients with elevated body mass index (BMI) are at risk of postoperative cerebrospinal fluid (CSF) leak following transsphenoidal procedures, reports a Singapore study. This is true even in an Asian population, where the definition of obesity varied from international standards. Therefore, BMI should be considered in the clinical decision-making process prior to such procedures.
Having both pre-existing type 2 diabetes (T2D) and chronic kidney disease (CKD) appears to raise the risk of all-cause and cardiovascular disease (CVD)-specific mortality in patients with heart failure, according to results of a Singapore study.
Perirenal fat is associated with carotid intima-media thickness, especially among overweight and obese children, and may thus represent a useful parameter for evaluating cardiovascular risk in the paediatric population, according to a study.
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
Patients with acromegaly, a rare disease caused by hypersecretion of growth hormone (GH) usually from a pituitary adenoma, have a slightly elevated risk of cancer, according to a cohort study. This finding is supported by a meta-analysis, but selection bias is present in some earlier studies.
Diabetes appears to significantly increase the risk of cataract detection, particularly in young patients, a recent study has shown.
Among patients with drug-refractory atrial fibrillation (AF), obesity is associated with lower pulmonary vein isolation treatment success but not with increased adverse events, as reported in a study.
Special Reports
At the recent ‘Reinforced for the Glycaemic Challenge’ symposium held at Shangri-la Hotel, Kuala Lumpur, Associate Professor Dr Alexander Tan, Professor Dr Chee Kok Han and Dr Chan Siew Pheng shared their insights into the importance of achieving glycaemic control in patients with type 2 diabetes mellitus (T2DM), while simultaneously providing them with cardiovascular protection.
At a recent lunch symposium held in conjunction with the 1st Malaysian Advances in Women’s Health Congress 2016, Professor Dr Jamiyah Hassan imparted clinical updates and strategies for the optimization of hormone replacement therapy in menopausal women. Highlights from her presentation are summarized below.
At the recent Malaysian Osteoporosis Society 2016 Clinical Practice Guideline (CPG) Meeting held on the 8th of October 2016 at Ibis Styles Ipoh, Dr Hew Fen Lee and Professor Dr Chan Siew Pheng presented clinical guidance on the management of osteoporosis, and discussed whether the benefits of treatment outweigh the risks.
At the Diabetes Asia 2016 Conference organized by the National Diabetes Institute, Professor Jean Claude Mbanya presented the case for why gliclazide modified release (MR; Diamicron® MR, Servier) should be the treatment of choice for early and aggressive control of type 2 diabetes (T2D).
BASALOG – Insulin glargine (rDNA) 100 IU/mL soln for inj (cartridge) – CCM Pharmaceuticals
INVOKANA – Canagliflozin hemihydrate 100 mg and 300 mg FC tab – Johnson & Johnson (Janssen)
Preventing hypertension, diabetes, and obesity, which are the major risk factors for heart failure (HF), by ages 45 and 55 years may lower risks of incident HF and prolong HF-free survival, suggests data from the Cardiovascular Disease Lifetime Risk Pooling Project.
Conference Reports
Diabetes mellitus (DM) is increasingly diagnosed in younger individuals. This poses challenges such as long exposure to diabetes and its complications and the need for tailor-made treatment protocols that fit a specific group of diabetic patients.
Men with low total sperm count (TSC) have more issues to worry about other than fertility, according to an Italian study presented at ENDO 2018 in Chicago, Illinois, US, which identified an association between low TSC and poor metabolic, cardiovascular, and bone health.
Tooth loss or missing teeth due to decay or periodontal disease may suggest an increased risk of type 2 diabetes (T2D), according to a study presented at ENDO 2018 held in Chicago, Illinois, US.
The investigational oral synthetic androgen dimethandrolone undecanoate (DMAU) suppresses serum testosterone levels to near castrate levels and appears safe when taken once daily for a month, showing potential as a male contraceptive pill, according to a study.
Individuals with obesity but without diabetes experienced significant weight reduction with daily doses of the glucagon-like peptide-1 receptor agonist semaglutide, according to a recent study presented at ENDO 2018.
The use of a hybrid closed-loop insulin pump, which has shown promise in improving glycaemic outcomes in adolescents and adults with type 1 diabetes, may also be beneficial in children, according to a study presented at ENDO 2018.
Oral micronized progesterone (OMP) may provide relief for perimenopausal women who had hot flashes and night sweats, according to a study presented at the ENDO 2018 Annual Meeting.
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