Irritable bowel syndrome and functional dyspepsia, along with most of their major subtypes except constipation-predominant IBS, appear to go hand in hand with a range of sleep disturbances, as reported in a study.
In managing functional dyspepsia, itopride and acotiamide, tricyclic antidepressants, histamine‐2 receptor antagonists, proton pump inhibitors, and the antipsychotic sulpiride or levosulpiride all prove to be more effective than placebo, according to the results of a meta-analysis.
Patients with inadequate response to proton pump inhibitors and prokinetics for functional dyspepsia may derive benefit from low doses of the tricyclic antidepressant (TCA) imipramine, according to a recent study from Hong Kong.
Helicobacter pylori (H. pylori) infection is associated with conditions such as gastritis, peptic ulcer, gastric cancer, and certain types of lymphoma. A common presenting complaint among all these H. pylori-related illnesses is dyspepsia. Dr Desmond Wai from the Desmond Wai Liver and Gastrointestinal Diseases Centre, Mount Elizabeth Novena Specialist Centre, Singapore, speaks on the important role general practitioners (GPs) play in recognizing, diagnosing, and treating H. pylori.
Recently, randomized controlled trials and guidelines have brought to light the benefits of extending the duration of H. pylori treatment. Below are summaries of guidelines and trials examining the regimens used to manage the infection.