The risk of cardiovascular (CV) events is lower in psoriasis patients treated with tumour necrosis factor-alpha inhibitors (TNFi) than in those treated with phototherapy, according to a recent US study.
Dupilumab, the fully human anti-interleukin-4 receptor α monoclonal antibody indicated for the treatment of atopic dermatitis, appeared to improve lung function, reduce exacerbations, and decrease oral corticosteroid use in individuals with moderate-to-severe asthma, according to two phase III trials presented at ATS 2018.
Infants born very preterm appear to have a lower risk of eczema, according to a recent meta-analysis. However, further studies are required to confirm the findings and to understand the underlying mechanisms.
New drug applications approved by US FDA as of 16 - 31 May which
includes New Molecular Entities (NMEs) and new biologics. It does not
include Tentative Approvals. Supplemental approvals may have occurred
since the original approval date.
Graft-versus-host-disease (GVHD), which often presents with a skin rash, is an extremely rare but potentially fatal condition that may occur after solid organ transplantation (SOT), according to a systematic review.
Patients with haematologic malignancies are significantly more likely to receive inpatient dermatology consultations, a recent study has shown. Moreover, inflammatory diseases, infections and drug reactions are the most common classes of dermatologic conditions in hospitalized cancer patients.
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
A treatment regimen combining daratumumab plus bortezomib, melphalan and prednisone markedly extends progression-free survival in patients with multiple myeloma, inducing deep responses and demonstrating acceptable tolerability regardless of baseline renal function, according to the results of the phase III ALCYONE study.
Segmentectomy and lobectomy confer similar overall survival (OS) and lung cancer-specific survival (LCSS) among patients with primary nonsmall cell lung cancer (NSCLC) of ≤20 mm without lymph node or distant metastasis, a recent study has shown.