Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.
There is a high prevalence of metabolic syndrome (MetS) in patients with psoriasis in Singapore, which is nearly threefold higher than the general population, a study has shown. However, no association exists between disease severity and presence of MetS.
The new first-in-class monoclonal antibody dupilumab (Dupixent®, Sanofi) is now available in Malaysia. The agent is indicated for use in adults with moderate-to-severe atopic dermatitis (AD), whose disease is not adequately controlled by topical therapies or when those therapies are contraindicated.
Disease severity, rather than sociodemographic factors, is the strongest determinant of health-related quality of life (HRQOL) in children with atopic dermatitis and their caregivers, according to a recent Singapore study.
New drug application approved by US FDA as of 16 - 31 October 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
A dermatology outpatient setting in Singapore has seen a moderately high prevalence of steroid phobia, with gender differences for topical corticosteroids (TCS) phobia, according to a study. Misconceptions also exist regarding the side effects of steroids.
New drug applications approved by US FDA as of 01 - 15 October 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Aqueous cream moisturizers that do not contain sodium lauryl sulphate (SLS) are less irritating to the skin than SLS-containing ones, while achieving similar levels of hydration and skin barrier integrity, according to a recent Singapore study.
Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.
Use of isatuximab (Isa) in combination with pomalidomide and dexamethasone (PomDex) appears to lead to more favourable outcomes in elderly patients with relapsed/refractory multiple myeloma (RRMM) as compared with PomDex alone, according to the results of a subgroup analysis of the ICARIA-MM trial presented at the 61st Annual Meeting of the American Society of Hematology (ASH 2019).