Hospitalized adults with COVID-19, as opposed to those with other acute viral infections, normally present with mucocutaneous eruptions, which may indicate a more severe course of illness, suggests a recent study.
The oral Janus kinase (JAK) inhibitor abrocitinib, otherwise called jakinib, does well in patients 12–17 years of age with atopic dermatitis (AD) in the phase III JADE TEEN study, providing instant itch relief.
Tedizolid is a safe and effective treatment option for adolescents with acute bacterial skin and skin structure infections (ABSSSIs), particularly those with S. aureus-susceptible strains, a study has shown.
Subgroup analyses of the phase III APeX-2 trial presented at AAAAI 2021 showed that use of the oral plasma kallikrein inhibitor berotralstat led to consistent reductions in attack frequency in patients with hereditary angioedema (HAE), irrespective of baseline attack rates and prior prophylaxis.
Romilkimab – a novel engineered, humanized immunoglobulin(Ig)-G4 antibody – delivers significant skin benefits for individuals with early diffuse cutaneous systemic sclerosis (dcSSc), a subtype of SSc, a phase II proof-of-concept study has shown.
The efficacy and safety of long-term tildrakizumab are comparable and maintained without evidence of reduced durability of response through 148 weeks of treatment in patients with and without metabolic syndrome (MetS), results from two phase III trials have shown.
There is a high burden of paediatric eczema in the primary care setting. Dr Liew Hui Min, a consultant dermatologist from SOG-HM Liew Skin & Laser Clinic at Gleneagles Hospital, Singapore, shares her insights with Pearl Toh on how to manage paediatric eczema in the primary care setting.
Upadacitinib monotherapy improved symptoms and quality of life (QoL) in adolescents and adults with moderate-to-severe atopic dermatitis (AD), according to the phase III Measure Up 1 and 2 studies presented at EADV 2020.
The novel, humanized IgG1 monoclonal antibody risankizumab was superior to ustekinumab and placebo in reducing and potentially eliminating symptoms of moderate-to-severe chronic plaque psoriasis, according to two replicate phase III trials.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.