The addition of the anti-interleukin (IL)-13 monoclonal antibody lebrikizumab to a rigorous topical corticosteroid (TCS) regimen provided significant dermatologic benefit among patients with moderate-to-severe atopic dermatitis (AD), the TREBLE* study shows.
Daily doses of the probiotic strains Bifidobacterium lactis CECT 8145, Bifidobacterium longum CECT 7347, and Lactobacillus casei CECT 9104 may reduce the SCORAD* index and need for topical steroids in children with moderate atopic dermatitis, according to a small study from Spain.
Adjunct Associate Professor Chong Wei Sheng, Head of the Psoriasis Unit at the National Skin Centre, Singapore, speaks to Roshini Claire Anthony on the vital role played by primary care physicians (GPs) in tackling psoriasis.
Treatment with adalimumab vs placebo for 26 weeks leads to significant improvements in the primary and all ranked secondary endpoints, as well as in signs and symptoms of moderate-to-severe nail psoriasis, with no new safety risks involved, reports a recent phase III trial.
Individuals with obesity and high abdominal fat mass appear to have a twofold increased risk of developing psoriasis, as shown in a study. Long-term weight gain of ≥10 kg is also associated with a substantially increased risk.
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.
Eczema (atopic dermatitis) is a chronic inflammatory skin disease that
can present in many different forms. However, it is principally
characterized by dry skin, intense itching, and the presence of
inflammatory skin lesions. [J Eur Acad Dermatol Venereol
2016;30:604-618; N Engl J Med 2008;358:1483-1494; Lancet
New drug applications approved by US FDA as of 1 - 15 December 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Striae may occur during pregnancy, puberty or rapid weight gain. Treatment options include laser, surgery and prescription-only medication, and may be relatively costly. A cheaper option that may be effective in improving the appearance of striae is the use of topical products.